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Table 3 Multiple regression of the effect of age, sex and new pathology on change in (a) mental component summary (MCS) from baseline to 10-year follow-up, controlling for baseline MCS (R2 = 0.30), (b) physical component summary (PCS) from baseline to 10-year follow-up, controlling for baseline PCS (R2 = 0.30)

From: Health-related quality of life in Marfan syndrome: a 10-year follow-up

Predictor variable

Regression coefficient, β

95% CI for β

t

p value

Lower bound

Upper bound

(a)

 Age

0.15

− 0.12

0.41

1.10

0.28

 Sex

1.82

− 4.51

8.14

0.58

0.57

 New cardiovascular pathology

0.94

− 5.0

6.86

0.32

0.75

 New non-cardiovascular pathology

− 0.42

− 6.54

5.70

− 0.14

0.89

 MCS

− 0.50

− 0.74

− 0.25

− 4.00

0.000

(b)

 Age

− 0.33

− 0.60

− 0.06

− 2.46

0.02

 Sex

− 0.42

− 7.74

6.89

− 0.12

0.91

 New cardiovascular pathology

− 3.10

− 9.48

3.27

− 0.98

0.33

 New non-cardiovascular pathology

0.47

− 6.04

6.97

0.14

0.89

 PCS

− 0.57

− 0.90

− 0.24

− 3.46

0.001