Skip to main content

Table 1 Demographics and clinical characteristics at study enrolment, stratified by patient group

From: Health-related quality of life and work productivity in UK patients with HER2-positive breast cancer: a cross-sectional study evaluating the relationships between disease and treatment stage

  Group 1 Group 2 Group 3
(n = 89) (n = 108) (n = 102)
Patient characteristics
 Mean (SD) age (years) 55.0 (11.1) 57.7 (10.6) 55.3 (11.2)
 Ethnicitya (n, %)
  White British 75 (84.3%) 101 (93.5%) 83 (81.4%)
  Other 10 (11.2%) 7 (6.5%) 15 (14.7%)
 Educationb
  GCSE (or equivalent) or higher (n, %) 66 (74.2%) 81 (75.0%) 81 (79.4%)
  No formal qualifications 21 (23.6%) 26 (24.1%) 19 (19.6%)
 ≥ 1 clinically significant comorbiditiesc, (n, %) 11 (12.4%) 10 (9.3%) 15 (14.7%)
Disease characteristics
 Tumour stage (n, %)
  Stage I 20 (22.5%) 25 (23.1%) 0 (0.0%)
  Stage II 54 (60.7%) 53 (49.1%) 0 (0.0%)
  Stage III 14 (15.7%) 29 (26.9%) 0 (0.0%)
  Stage IV 0 (0.0%) 0 (0.0%) 101 (99.0%)
  Not recorded 1 (1.1%) 0 (0.0%) 1 (1.0%)
 Hormone receptor-positive (n, %)
  Yes 64 (71.9%) 84 (77.8%) 74 (72.5%)
  No 25 (28.1%) 24 (22.2%) 26 (25.5%)
  Not known 0 (0.0%) 0 (0.0%) 2 (2.0%)
 Median (IQR) time since early BC diagnosis (months) 9.0 (6.0) 45.0 (32.0) (n = 103) 79.5 (82.0) (n = 71)
 Median (IQR) time since metastatic BC diagnosis (months)    30.0 (37.0)
 Type of metastatic BC diagnosis (n, %)
  De novo 27 (26.5%)
  Relapsed 75 (73.5%)
 Sites of metastatic BC disease (n, %)
  Non-visceral 23 (22.5%)
  Visceral involvement 77 (75.5%)
  Visceral involvement unknown 2 (2.0%)
  No CNS involvement 71 (69.6%)
  CNS involvement 25 (24.5%)
  CNS involvement unknown 6 (5.9%)
  1. n, numbers shown where data were not available or not applicable for all patients
  2. GCSE General Certificate of Secondary Education, IQR interquartile range, SD standard deviation, CNS central nervous system
  3. aOther ethnicities observed included “Other White”, “African”, “Caribbean”, “other Black”, “Chinese”, “Indian”, “Other Asian, and “Other ethnic group”; n = 4 patients in Group 1 and n = 4 patients in Group 3 did not state their ethnic group
  4. bn = 2 patients in Group 1, n = 1 patient in Group 2 and n = 2 patients in Group 3 did not state their education level
  5. cExcludes tumour and metastases