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Table 7 Factors related to improved or reduced quality of life in breast cancer patients and survivors

From: Health-related quality of life in breast cancer patients: review of reviews from 2008 to 2018

Factors that might improve quality of life Factors that might deteriorate quality of life
Reduction of radiation-induced skin toxicity using simultaneous integrated boost, accelerated partial breast irradiation, and prone positioning Adjuvant endocrine therapy-related side effects including vasomotor symptoms such as hot flashes
Adjuvant chemotherapy and radiotherapy in the elderly with solid tumors Targeted therapy-related side effects: diarrhoea and skin rash in the adjuvant and metastatic settings for HER2+ breast cancer
Oncoplastic breast surgery Body image after mastectomy
Both immediate and delayed breast reconstruction in long-term Chemotherapy-induced alopecia
Better preoperative counseling and informed decision-making Disturbances in sexual life
Physical activity interventions such as yoga, exercise, physical self-management, complementary exercise, art therapies, and mind–body exercise therapy Less social support and unmet needs
Treatment of lymphedema: manual lymphatic drainage Lymphedema affecting woman’s physical, psychological, and emotional well-being
Psychoeducational support or receiving social support in early stage breast cancer Premature menopause, menopausal symptoms, and infertility
Cognitive behavioral therapy Comorbid depression which significantly increases the burden of distress and dysfunction