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Table 5 Health-related quality of life in different levels of physical activity and sedentary time among CSs with ≥ 3 CCD (n = 464)

From: The association between physical activity, sedentary time and health-related quality of life in cancer survivors

Scales Physical activity Sedentary time
Mean (SD) Adjusted mean difference of scores (95% CI) Mean (SD) Adjusted mean difference of scores (95% CI)
Low (n = 72) Moderate (n = 140) Pa High (n = 252) Pa < 4 h/d (n = 246) 4–6 h/d (n = 152) Pa ≥ 6 h/d (n = 66) Pa
EORTC QLQ-C30
 Physical function 78.63 ± 17.43 0.11(− 4.77, 4.56) 0.965 0.05(− 4.33, 4.43) 0.983 79.51 ± 15.40 − 1.82(− 4.85, 1.22) 0.241 − 3.75(− 10.64, 3.14) 0.285
 Role function 91.40 ± 17.61 0.90(− 5.91, 4.12) 0.726 1.43(− 3.28, 6.13) 0.552 92.92 ± 16.93 − 1.83(− 5.12, 1.46) 0.275 − 1.89(− 9.45, 5.67) 0.623
 Emotional function 82.76 ± 19.23 0.31(− 7.56, 2.94) 0.387 0.67(− 4.25, 5.60) 0.788 82.00 ± 17.71 − 0.12(− 3.60, 3.35) 0.944 0.48(− 7.51, 8.47) 0.906
 Cognitive function 80.23 ± 17.31 − 2.99(− 8.94, 2.97) 0.325 − 3.87(− 9.46, 1.72) 0.174 76.88 ± 21.42 0.28(− 3.63, 4.19) 0.888 − 3.56(− 12.55, 5.42) 0.436
 Social function 81.97 ± 20.24 − 4.53(− 11.51, 2.46) 0.203 − 4.06(− 10.62, 2.49) 0.224 78.66 ± 24.82 − 1.45(− 6.06, 3.17) 0.538 − 3.14(− 13.74, 7.47) 0.562
 Global health/QoL 67.57 ± 24.09 − 1.15(− 7.91, 5.62) 0.739 − 0.32(− 6.67, 6.03) 0.920 68.28 ± 24.09 − 3.02(− 7.48, 1.44) 0.183 − 2.04(− 12.29, 8.21) 0.696
 Fatigue 28.31 ± 20.64 0.79(− 5.35, 6.92) 0.801 0.92(− 4.84, 6.68) 0.753 29.94 ± 21.68 0.46(− 3.56, 4.48) 0.823 7.97(− 1.27, 17.21) 0.091
 Nausea and vomiting 5.49 ± 13.02 − 2.51(− 5.46, 0.44) 0.096 − 1.96(− 4.73, 0.81) 0.164 2.77 ± 8.50 2.27(0.34, 4.21) 0.021 0.25(− 4.20, 4.69) 0.913
 Pain 14.47 ± 18.74 7.18(1.12, 13.25) 0.020 4.31(− 1.39, 10.00) 0.138 18.60 ± 20.39 2.64(− 1.37, 6.65) 0.197 6.44(− 2.78, 15.65) 0.171
 Dyspnoea 16.35 ± 20.65 4.78(− 1.80, 11.35) 0.154 1.91(− 4.26, 8.08) 0.544 19.32 ± 23.93 0.81(− 3.50, 5.13) 0.712 − 1.45(− 11.37, 8.46) 0.774
 Insomnia 27.03 ± 26.79 2.96(− 5.53, 11.44) 0.494 0.86(− 7.11, 8.82) 0.833 28.24 ± 27.81 2.30(− 3.23, 7.84) 0.414 3.25(− 9.47, 15.98) 0.615
 Appetite loss 8.66 ± 17.94 0.83(− 4.59, 6.25) 0.763 0.47(− 4.62, 5.56) 0.856 8.45 ± 16.67 2.22(− 1.32, 5.76) 0.218 − 0.27(− 8.40, 7.86) 0.948
 Constipation 6.50 ± 15.75 6.01(0.01, 12.02) 0.050 6.45(0.81, 12.08) 0.025 9.94 ± 18.86 2.26(− 1.66, 6.18) 0.257 4.16(− 4.85, 13.16) 0.365
 Diarrhea 12.12 ± 20.11 2.89(− 3.15, 8.93) 0.348 − 2.07(− 7.74, 3.60) 0.473 10.74 ± 18.32 2.75(− 1.21, 6.72) 0.173 2.20(− 6.91, 11.30) 0.636
 Financial difficulties 28.01 ± 28.86 4.22(− 4.79, 13.23) 0.358 3.33(− 5.13, 11.00) 0.439 32.47 ± 31.37 5.64(− 0.30, 11.59) 0.063 − 2.74(− 16.41, 10.92) 0.693
  1. Italic face P < 0.05
  2. CS cancer survivor, CCD comorbid chronic disease
  3. aAdjusted for gender, age, BMI, education, marital status, household per capita income, time since diagnosis, recurrence, and metastasis