Table 4 Health-related quality of life in different levels of physical activity and sedentary time among CSs with 1–2 CCD (n = 694)
Scales | Physical activity | Sedentary time | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean (SD) | Adjusted mean difference of scores (95% CI) | Mean (SD) | Adjusted mean difference of scores (95% CI) | |||||||
Low (n = 95) | Moderate (n = 163) | Pa | High (n = 436) | Pa | < 4 h/d (n = 386) | 4–6 h/d (n = 209) | Pa | ≥ 6 h/d (n = 99) | Pa | |
EORTC QLQ-C30 | ||||||||||
 Physical function | 78.28 ± 19.99 | 3.43(− 0.40, 7.26) | 0.079 | 6.48(3.11, 9.84) |  < 0.001 | 83.69 ± 14.32 | − 1.62(− 3.89, 0.64) | 0.160 | − 7.58(− 12.86, − 2.30) | 0.005 |
 Role function | 90.09 ± 17.43 | 4.92(1.38, 8.45) | 0.007 | 5.24(2.14, 8.34) | 0.001 | 94.23 ± 12.64 | 0.02(− 2.12, 2.16) | 0.988 | − 5.78(− 10.86, − 0.70) | 0.026 |
 Emotional function | 82.67 ± 18.41 | 4.07(− 0.19, 8.32) | 0.061 | 2.94(− 0.79, 6.68) | 0.123 | 84.86 ± 16.73 | 1.03(− 1.56, 3.63) | 0.434 | − 2.95(− 9.10, 3.21) | 0.347 |
 Cognitive function | 78.38 ± 20.40 | 2.07(− 2.58, 6.73) | 0.383 | 1.89(− 2.20, 5.98) | 0.366 | 79.51 ± 19.07 | 0.49(− 2.34, 3.32) | 0.734 | − 1.05(− 7.76, 5.66) | 0.759 |
 Social function | 75.43 ± 22.34 | 8.32(2.62, 14.02) | 0.004 | 6.07(1.06, 11.07) | 0.018 | 81.08 ± 22.62 | − 1.42(− 4.89, 2.06) | 0.423 | − 5.05(− 13.30, 3.20) | 0.230 |
 Global health/QoL | 70.30 ± 22.82 | 0.88(− 4.78, 6.54) | 0.760 | 2.70(− 2.28, 7.67) | 0.287 | 72.28 ± 21.89 | − 2.37(− 5.80, 1.06) | 0.175 | − 1.27(− 9.42, 6.88) | 0.759 |
 Fatigue | 26.65 ± 20.61 | − 1.08(− 6.11, 3.95) | 0.674 | − 1.07(− 5.49, 3.35) | 0.635 | 27.38 ± 20.37 | − 0.79(− 3.85, 2.28) | 0.615 | 7.33(0.06, 14.61) | 0.048 |
 Nausea and vomiting | 5.28 ± 11.36 | − 3.01(− 5.08, − 0.93) | 0.005 | − 2.98(− 4.81, − 1.16) | 0.001 | 2.54 ± 7.95 | 0.12(− 1.14, 1.38) | 0.854 | − 0.61(− 3.61, 2.39) | 0.690 |
 Pain | 15.45 ± 18.64 | − 4.36(− 8.70, − 0.02) | 0.049 | − 2.81(− 6.62, 1.00) | 0.148 | 13.62 ± 16.91 | − 0.64(− 3.27, 1.99) | 0.633 | 5.31(− 0.93, 11.55) | 0.095 |
 Dyspnoea | 18.42 ± 21.61 | − 5.76(− 10.86, − 0.66) | 0.027 | − 6.45(− 10.93, − 1.97) | 0.005 | 13.68 ± 19.61 | − 0.06(− 3.14, 3.02) | 0.970 | 5.07(− 2.25, 12.39) | 0.174 |
 Insomnia | 24.44 ± 27.85 | 0.81(− 5.94, 7.57) | 0.813 | − 3.46(− 9.39, 2.48) | 0.253 | 21.48 ± 26.06 | 4.30(0.20, 8.40) | 0.040 | 11.39(1.65, 21.12) | 0.022 |
 Appetite loss | 11.12 ± 18.14 | − 3.42(− 7.64, 0.80) | 0.112 | − 4.11(− 7.81, − 0.41) | 0.030 | 6.75 ± 16.29 | 2.07(− 0.47, 4.61) | 0.110 | 2.46(− 3.57, 8.49) | 0.423 |
 Constipation | 10.04 ± 17.58 | − 0.75(− 2.93, 6.42) | 0.463 | − 2.78(− 6.89, 1.32) | 0.184 | 9.03 ± 18.00 | 1.34(− 1.50, 4.17) | 0.354 | − 3.48(− 10.21, 3.24) | 0.310 |
 Diarrhea | 11.95 ± 20.74 | − 2.23(− 6.92, 2.47) | 0.353 | − 3.02(− 7.15, 1.10) | 0.151 | 10.14 ± 17.70 | − 0.66(− 3.49, 2.17) | 0.647 | − 1.52(− 8.24, 5.20) | 0.656 |
 Financial difficulties | 33.81 ± 30.37 | − 8.90(− 16.71, − 1.08) | 0.026 | − 1.65(− 8.51, 5.22) | 0.638 | 29.59 ± 31.47 | 2.17(− 2.57, 6.91) | 0.370 | 6.37(− 4.89, 17.62) | 0.267 |