From: Determinants of health-related quality of life decline in interstitial lung disease
 | K-BILD total | VAS | ||||
---|---|---|---|---|---|---|
Beta | 95% CI | p value | Beta | 95% CI | p value | |
Baseline FVC% predicted | − 0.022 | [− 0.039;− 0.006] | 0.007 | − 0.034 | [− 0.051;− 0.017] |  < 0.0001 |
Baseline DLCO% predicted | − 0.018 | [− 0.042;0.006] | 0.131 | − 0.006 | [− 0.027;0.016] | 0.618 |
Baseline HRQL score | 0.095 | [0.057;0.134] |  < 0.0001 | 0.038 | [0.020;0.056] |  < 0.0001 |
Age | 0.024 | [− 0.015;0.062] | 0.234 | 0.035 | [0.000;0.070] | 0.048 |
Time since diagnosis | − 0.004 | [− 0.062;0.053] | 0.880 | − 0.019 | [− 0.074;0.036] | 0.497 |
Number of comorbidities | 0.018 | [− 0.189;0.224] | 0.868 | − 0.014 | [− 0.208;0.179] | 0.885 |
Female | 0.703 | [− 0.011;1.417] | 0.054 | 0.205 | [− 0.436;0.846] | 0.531 |
ILD subtype (ref = Other ILD) | ||||||
 IPF | − 0.979 | [− 1.873;− 0.084] | 0.032 | − 0.163 | [− 0.961;0.635] | 0.689 |
 Sarcoidosis | 0.169 | [− 0.89;1.228] | 0.755 | 0.525 | [− 0.461;1.510] | 0.297 |
Smoking (ref = non-smoker) | ||||||
 Current smoker | − 0.232 | [− 2.142;1.678] | 0.812 | 0.706 | [− 1.018;2.430] | 0.422 |
 Former smoker | − 0.172 | [− 0.855;0.512] | 0.623 | 0.100 | [− 0.547;0.748] | 0.761 |
 Immunosuppressant use | − 0.421 | [− 1.224;0.382] | 0.304 | − 0.274 | [− 1.008;0.460] | 0.464 |
Education (ref = higher) | ||||||
 Basic education | 0.302 | [− 0.499;1.104] | 0.459 | − 0.015 | [− 0.723;0.694] | 0.968 |
 Secondary education | 0.949 | [0.105;1.792] | 0.027 | − 0.312 | [− 1.086;0.461] | 0.428 |
 Unemployed | 0.151 | [− 0.830;1.133] | 0.763 | 0.498 | [− 0.409;1.405] | 0.282 |
 Center 2 (ref = center 1) | 1.302 | [0.482;2.124] | 0.002 | 0.335 | [− 0.354;1.024] | 0.340 |