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Table 2 Predictors of HRQL deterioration in K-BILD total score and VAS (weighted)

From: Determinants of health-related quality of life decline in interstitial lung disease

 

K-BILD total

VAS

Beta

95% CI

p value

Beta

95% CI

p value

Baseline FVC% predicted

− 0.022

[− 0.039;− 0.006]

0.007

− 0.034

[− 0.051;− 0.017]

 < 0.0001

Baseline DLCO% predicted

− 0.018

[− 0.042;0.006]

0.131

− 0.006

[− 0.027;0.016]

0.618

Baseline HRQL score

0.095

[0.057;0.134]

 < 0.0001

0.038

[0.020;0.056]

 < 0.0001

Age

0.024

[− 0.015;0.062]

0.234

0.035

[0.000;0.070]

0.048

Time since diagnosis

− 0.004

[− 0.062;0.053]

0.880

− 0.019

[− 0.074;0.036]

0.497

Number of comorbidities

0.018

[− 0.189;0.224]

0.868

− 0.014

[− 0.208;0.179]

0.885

Female

0.703

[− 0.011;1.417]

0.054

0.205

[− 0.436;0.846]

0.531

ILD subtype (ref = Other ILD)

 IPF

− 0.979

[− 1.873;− 0.084]

0.032

− 0.163

[− 0.961;0.635]

0.689

 Sarcoidosis

0.169

[− 0.89;1.228]

0.755

0.525

[− 0.461;1.510]

0.297

Smoking (ref = non-smoker)

 Current smoker

− 0.232

[− 2.142;1.678]

0.812

0.706

[− 1.018;2.430]

0.422

 Former smoker

− 0.172

[− 0.855;0.512]

0.623

0.100

[− 0.547;0.748]

0.761

 Immunosuppressant use

− 0.421

[− 1.224;0.382]

0.304

− 0.274

[− 1.008;0.460]

0.464

Education (ref = higher)

 Basic education

0.302

[− 0.499;1.104]

0.459

− 0.015

[− 0.723;0.694]

0.968

 Secondary education

0.949

[0.105;1.792]

0.027

− 0.312

[− 1.086;0.461]

0.428

 Unemployed

0.151

[− 0.830;1.133]

0.763

0.498

[− 0.409;1.405]

0.282

 Center 2 (ref = center 1)

1.302

[0.482;2.124]

0.002

0.335

[− 0.354;1.024]

0.340

  1. The figures in italics are results that are statistically significant with p < 0.05