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Table 4 Assessment of responsiveness of the EQ-5D-3L and the EQ-5D-5L measures to changes in the Barthel Index (n = 224)

From: Measurement properties of EQ-5D-3L and EQ-5D-5L in recording self-reported health status in older patients with substantial multimorbidity and polypharmacy

 

EQ-5D-3L at 6 months (mean)

EQ-5D-3L at 12 months (mean)

Difference between 12 and 6 months EQ-5D-3L (95% CI)

Effect size (Cohen’s D)a

n

% reporting 3L score increase

Barthel Index

 Improved

0.68

0.83

0.16 (0.07 to 0.25)

0.66**

31

55

 No change

0.89

0.87

− 0.02 (− 0.05 to 0.02)

− 0.09

142

25

 Worsened

0.74

0.66

− 0.08 (− 0.16 to 0.00)

− 0.30*

50

28

 

EQ-5D-5L at 6 months (mean)

EQ-5D-5L at 12 months (mean)

Difference between 12 and 6 months EQ-5D-5L (95% CI)

Effect size (Cohen’s D)

n

% reporting 5L score increase

Barthel Index

 Improved

0.68

0.81

0.13 (0.07 to 0.20)

0.66***

31

59

 No change

0.87

0.86

− 0.01 (− 0.04 to 0.02)

− 0.05

142

32

 Worsened

0.73

0.65

− 0.09 (− 0.14 to − 0.03)

− 0.36**

50

32

  1. aCohen’s D effect sizes of between 0.2 and 0.5 are considered small, 0.5 and 0.8 moderate and > 0.8 large
  2. *p < 0.05; **p < 0.01; ***p < 0.001