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Table 4 Assessment of responsiveness of the EQ-5D-3L and the EQ-5D-5L measures to changes in the Barthel Index (n = 224)

From: Measurement properties of EQ-5D-3L and EQ-5D-5L in recording self-reported health status in older patients with substantial multimorbidity and polypharmacy

  EQ-5D-3L at 6 months (mean) EQ-5D-3L at 12 months (mean) Difference between 12 and 6 months EQ-5D-3L (95% CI) Effect size (Cohen’s D)a n % reporting 3L score increase
Barthel Index
 Improved 0.68 0.83 0.16 (0.07 to 0.25) 0.66** 31 55
 No change 0.89 0.87 − 0.02 (− 0.05 to 0.02) − 0.09 142 25
 Worsened 0.74 0.66 − 0.08 (− 0.16 to 0.00) − 0.30* 50 28
  EQ-5D-5L at 6 months (mean) EQ-5D-5L at 12 months (mean) Difference between 12 and 6 months EQ-5D-5L (95% CI) Effect size (Cohen’s D) n % reporting 5L score increase
Barthel Index
 Improved 0.68 0.81 0.13 (0.07 to 0.20) 0.66*** 31 59
 No change 0.87 0.86 − 0.01 (− 0.04 to 0.02) − 0.05 142 32
 Worsened 0.73 0.65 − 0.09 (− 0.14 to − 0.03) − 0.36** 50 32
  1. aCohen’s D effect sizes of between 0.2 and 0.5 are considered small, 0.5 and 0.8 moderate and > 0.8 large
  2. *p < 0.05; **p < 0.01; ***p < 0.001