|
EQ-5D-3L at 6 months (mean)
|
EQ-5D-3L at 12 months (mean)
|
Difference between 12 and 6 months EQ-5D-3L (95% CI)
|
Effect size (Cohen’s D)a
|
n
|
% reporting 3L score increase
|
---|
3L-VAS
|
Improved
|
0.92
|
0.93
|
0.01 (− 0.03 to 0.05)
|
0.15
|
10
|
30
|
No change
|
0.87
|
0.81
|
− 0.06 (− 0.19 to 0.07)
|
− 0.22
|
25
|
24
|
Worsened
|
0.85
|
0.84
|
− 0.01 (− 0.08 to 0.06)
|
− 0.06
|
20
|
15
|
|
EQ-5D-5L at 6 months (mean)
|
EQ-5D-5L at 12 months (mean)
|
Difference between 12 and 6 months EQ-5D-5L (95% CI)
|
Effect size (Cohen’s D)
|
n
|
% reporting 5L score increase
|
---|
5L-VAS
|
Improved
|
0.90
|
0.91
|
0.01 (− 0.02 to 0.04)
|
0.14
|
10
|
30
|
No change
|
0.83
|
0.81
|
− 0.02 (− 0.10 to 0.07)
|
− 0.06
|
25
|
28
|
Worsened
|
0.84
|
0.85
|
0.01 (− 0.06 to 0.08)
|
0.05
|
20
|
20
|
- aCohen’s D effect sizes of between 0.2 and 0.5 are considered small, 0.5 and 0.8 moderate and > 0.8 large