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Table 5 Prospective associations of composite variable categories defined by latent classes (Table A9A) and metabolic syndrome (Table A9B), respectively, and physical activity status at SAPALDIA3, with median levels of HRQoL at SAPALDIA4, adjusted for respective HRQoL domain at SAPALDIA3

From: The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome

N = 902 General Health (GH) Physical Functioning (PF) Bodily Pain (BP) Vitality (VT) Mental Health (MH)
  Coefficient
(95% CI)
P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value Coefficient (95% CI) P-value
5A. Latent classes
+ Physical Activity
Healthy & active Reference          
Healthy & inactive −0.36 (−2.56; 2.84) 0.749 − 0.24 (− 1.69; 1.21) 0.741 0.00 (−4.69; 4.69) 1.000 − 0.32 (−3.64; 3.00) 0.849 0.57 (− 3.69; 4.83) 0.792
At risk & active −2.02 (− 4.50; 0.40) 0.100 − 0.69 (− 1.81; 0.42) 0.223 0.00 (− 1.72; 1.72) 1.000 −1.00 (− 3.11; 1.13) 0.359 −0.57 (− 2.20; 1.06) 0.492
At risk & inactive −0.92 (− 4.05; 2.21) 0.564 − 1.03 (− 2.52; − 0.46) 0.175 −0.62 (− 4.95; 3.71) 0.778 − 1.29 (− 4.93; 2.34) 0.485 − 2.29 (− 4.34; − 0.23) 0.029
Unhealthy & active − 1.63 (− 4.03; 0.76) 0.181 −2.57 (− 4.32; − 0.81) 0.004 −0.69 (− 4.71; 3.33) 0.737 − 0.13 (− 2.70; 2.45) 0.922 0.00 (− 2.64; 2.64) 1.000
Unhealthy & inactive −4.95 (− 7.01; − 2.90) < 0.001 − 3.55 (− 8.41; 1.31) 0.152 −5.42 (− 15.45; 4.61) 0.289 0.04 (− 3.71; 3.80) 0.981 1.71 (− 3.88; 7.31) 0.547
5B. Metabolic Syndrome
+ Physical Activity
No MetS & active Reference          
No MetS & inactive 1.03 (− 1.28; 3.34) 0.381 0.32 (−0.79; 1.44) 0.569 0.00 (−4.67; 4.67) 1.000 1.64 (−0.83; 4.11) 0.192 0.55 (−2.08; 3.18) 0.663
MetS & active −0.43 (−2.38; 1.53) 0.668 − 1.79 (− 2.80; − 0.79) < 0.001 0.00 (− 1.27; 1.27) 1.000 1.74 (− 0.16; 3.64) 0.072 1.92 (0.31: 3.53) 0.020
MetS & inactive −4.83 (−7.89; − 1.78) 0.002 − 2.48 (− 4.46; − 0.50) 0.014 − 1.38 (−5.42; 2.66) 0.504 − 2.19 (− 5.80; 1.43) 0.235 0.51 (− 2.97; 3.98) 0.776
  1. CI = Confidence interval
  2. Differences in median levels were analysed with quantile regression models; a negative effect indicates a lower median score
  3. Adjusted for sex, age, education level, study area, and HRQoL at SAPALDIA3
  4. Categorized according to WHO Physical Activity Guidelines
  5. Inactive: < 150 min of MPA and < 75 VPA per week
  6. Sufficiently active: > 150 min of MPA or > 75 VPA per week
  7. Metabolic syndrome: Any three of the following values: Blood glucose ≥5.6 mmol/L (Hba1C ≥5.7% in SAPALDIA4); waist circumference ≥ 94 cm in men & ≥80 cm in women; systolic blood pressure ≥ 130 or diastolic blood pressure ≥ 85; hdl < 1.0 mmol/L in men & < 1.3 mmol/L in women; triglycerides ≥1.7 mmol/L