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Table 4 Cross-sectional adjusted associations of latent classes (4A) and metabolic syndrome (4B) with HRQoL domains, without and with additional adjustment for physical activity (SAPALDIA4)

From: The modifying role of physical activity in the cross-sectional and longitudinal association of health-related quality of life with physiological functioning-based latent classes and metabolic syndrome

N = 1124 General Health (GH) Physical
Functioning (PF)
Bodily Pain (BP) Vitality (VT) Mental Health (MH)
  Coefficient
(95% CI)
P-value Coefficient (95% CI) P-value Coefficient
(95% CI)
P-value Coefficient
(95% CI)
P-value Coefficient
(95% CI)
P-value
4A. Latent classes           
Healthy Reference          
At risk −0.22 (−2.57; 2.14) 0.855 −1.01 (− 2.05; − 0.03) 0.057 − 1.39 (− 4.17; 1.40) 0.329 −0.00 (− 2.00; 2.00) 1.000 −0.30 (− 1.97; 1.16) 0.721
Unhealthy −3.06 (− 5.51; − 0.58) 0.015 − 5.64 (− 6.98; − 4.30) < 0.001 −9.14 (− 13.91; − 4.38) < 0.001 − 2.50 (− 5.22; − 0.22) 0.072 − 1.10 (− 3.37; 1.16) 0.339
+ Physical Activity
Healthy Reference          
At risk 0.12 (− 2.28; 2.52) 0.924 − 0.73 (− 1.65; 0.18) 0.115 −1.43 (−4.26; 1.39) 0.319 − 2.50 (− 4.52; − 0.48) 0.092 0.00 (− 1.93; 1.93) 1.000
Unhealthy − 2.64 (− 5.29; 0.00) 0.050 − 5.00 (− 6.59; − 3.41) < 0.001 −7.82 (− 12–48; − 3.16) 0.001 − 2.50 (− 4.76–0.24) 0.030 0.00 (− 2.46; 2.46) 1.000
Physical Activity
(Sufficiently active)
4.27 (1.98; 6.56) < 0.001 3.92 (2.50; 5.34) < 0.001 4.27 (0.67; 7.87) 0.020 7.50 (5.28; 9.71) < 0.001 4.00 (1.50; 6.50) 0.002
4B. Metabolic Syndrome (MetS)
No MetS Reference          
Yes MetS −3.47 (−5.41; −1.54) < 0.001 − 3.46 (−4.69; −2.22) < 0.001 − 2.69 (−6.39; 1.01) 0.153 − 5.00 (−7.18; − 2.82) < 0.001 − 0.21 (− 1.99; 1.57) 0.817
+ Physical Activity
Yes MetS − 3.18 (− 5.27; − 1.08) 0.003 − 2.40 (− 3.73; − 1.08) < 0.001 − 2.92 (− 6.23; 0.39) 0.084 −2.50 (− 4.12; − 0.88) 0.003 0.00 (−1.76; 1.76) 1.000
Physical Activity
(Sufficiently active)
4.11 (1.69; 6.53) 0.001 4.03 (2.60; 5.45) < 0.001 5.70 (2.88: 8.52) < 0.001 7.50 (5.32; 9.68) < 0.001 4.00 (1.44; 6.56) 0.002
  1. CI = Confidence interval
  2. Differences in median levels were analysed with quantile regression models; a negative effect indicates a lower median score
  3. Adjusted for sex, age, education level and study area
  4. Categorized according to WHO Physical Activity Guidelines
  5. Inactive: < 150 min of MPA and < 75 VPA per week
  6. Sufficiently active: > 150 min of MPA or > 75 VPA per week.
  7. Metabolic syndrome: Any three of the following values: Blood glucose ≥5.6 mmol/L (Hba1C ≥5.7% in SAPALDIA4); waist circumference ≥ 94 cm in men & ≥80 cm in women; systolic blood pressure ≥ 130 or diastolic blood pressure ≥ 85; hdl < 1.0 mmol/L in men & < 1.3 mmol/L in women; triglycerides ≥1.7 mmol/L