From: Gender differences in quality of life among patients with myasthenia gravis in China
Physical QoL | Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | |
Socio-demographic variables | ||||||
 Age | 0.04 (− 0.06 to 0.15) | 0.419 | 0.03 (− 0.07 to 0.14) | 0.522 | 0.04 (− 0.07 to 0.15) | 0.451 |
 Education | 1.12 (− 0.32 to 2.56) | 0.127 | 1.11 (− 0.33 to 2.55) | 0.130 | 1.07 (− 0.37 to 2.50) | 0.146 |
 Unemployment | − 4.82 (− 7.58 to − 2.07) | < 0.001 | − 4.70 (− 7.48 to − 1.92) | < 0.001 | − 4.61 (− 7.38 to − 1.84) | < 0.01 |
 Annual household income | 0.00 (0.00 to 0.00) | < 0.05 | 0.00 (0.00 to 0.00) | < 0.05 | 0.00 (0.00 to 0.00) | < 0.05 |
Diagnosis and treatment history | ||||||
 Thymectomy (0 = no; 1 = yes) | −2.70 (− 5.24 to − 0.16) | < 0.05 | − 2.72 (− 5.26 to − 0.18) | < 0.05 | − 2.81 (− 5.34 to − 0.27) | < 0.05 |
 MG exacerbations (0 = no; 1 = yes) | −7.71 (− 10.60 to − 4.82) | < 0.001 | − 7.71 (− 10.60 to − 4.82) | < 0.001 | − 7.71 (− 10.59 to − 4.83) | < 0.001 |
 Prednisone treatment (0 = never had prednisone) | ||||||
  Current prednisone | −3.12 (− 6.22 to − 0.01) | < 0.05 | − 3.14 (− 6.25 to − 0.03) | < 0.05 | −2.99 (− 6.09 to 0.11) | 0.059 |
  Past prednisone | −0.98 (− 4.69 to 2.72) | 0.603 | − 0.971 (− 4.68 to 2.74) | 0.607 | −0.86 (− 4.56 to 2.83) | 0.646 |
Number of comorbid conditions | 0.41 (−0.30 to 1.13) | 0.252 | 0.40 (− 0.31 to 1.11) | 0.272 | 1.25 (0.30 to 2.21) | < 0.05 |
Social support and Active lifestyle | ||||||
 Tangible support | −0.00 (− 0.07 to 0.07) | 0.972 | − 0.00 (− 0.07 to 0.07) | 0.990 | −0.00 (− 0.07 to 0.07) | 0.989 |
 Affectionate support | 0.06 (−0.07 to 0.18) | 0.364 | 0.06 (−0.06 to 0.18) | 0.333 | 0.07 (−0.06 to 0.19) | 0.284 |
 Positive social interaction | −0.03 (− 0.14 to 0.08) | 0.609 | − 0.03 (− 0.15 to 0.08) | 0.559 | −0.03 (− 0.15 to 0.08) | 0.549 |
 Emotional/information support | 0.02 (−0.08 to 0.11) | 0.718 | 0.02 (−0.07 to 0.11) | 0.664 | 0.02 (−0.08 to 0.11) | 0.753 |
 Active lifestyle | 0.27 (0.16 to 0.39) | < 0.001 | 0.27 (0.16 to 0.39) | < 0.001 | 0.27 (0.16 to 0.39) | < 0.001 |
MG-ADL | −4.39 (− 4.73 to − 4.05) | < 0.001 | −4.38 (− 4.73 to − 4.04) | < 0.001 | −4.36 (− 4.70 to − 4.02) | < 0.001 |
Gender (0 = male; 1 = female) |  |  | − 0.93 (− 3.73 to 1.87) | 0.516 | 0.93 (−2.19 to 4.06) | 0.557 |
Gender × Comorbiditiesa |  |  |  |  | −1.78 (−3.12 to −0.44) | < 0.01 |
Adjusted R-squared | 0.6364 | 0.6362 | 0.6389 |