Table 3 Results of multivariable regression analyses in overall QoL in MG-QOL15r
From: Gender differences in quality of life among patients with myasthenia gravis in China
Overall QoL | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | |
Socio-demographic variables | ||||||
 Age | 0.13 (0.02 to 0.24) | < 0.05 | 0.12 (0.01 to 0.23) | < 0.05 | 0.13 (0.02 to 0.24) | < 0.05 |
 Education | 1.19 (− 0.27 to 2.66) | 0.111 | 1.19 (− 0.28 to 2.66) | 0.113 | 1.14 (− 0.33 to 2.61) | 0.127 |
 Unemployment | − 4.99 (− 7.80 to − 2.18) | < 0.001 | − 4.87 (− 7.70 to − 2.03) | < 0.001 | − 4.78 (− 7.61 to − 1.96) | < 0.001 |
 Annual household income | 0.00 (0.00 to 0.00) | < 0.01 | 0.00 (0.00 to 0.00) | < 0.05 | 0.00 (0.00 to 0.00) | < 0.01 |
Diagnosis and treatment history | ||||||
 Thymectomy (0 = no; 1 = yes) | − 2.07 (− 4.66 to 0.52) | 0.118 | − 2.08 (− 4.68 to 0.51) | 0.115 | − 2.17 (− 4.75 to 0.42) | 0.100 |
 MG exacerbations (0 = no; 1 = yes) | − 8.49 (− 11.43 to − 5.54) | < 0.001 | − 8.49 (− 11.44 to − 5.54) | < 0.001 | − 8.49 (− 11.43 to − 5.55) | < 0.001 |
 Prednisone treatment (0 = never had prednisone) |  |  |  |  |  |  |
  Current prednisone | −3.83 (− 6.55 to − 0.21) | < 0.05 | − 3.40 (− 6.57 to − 0.23) | < 0.05 | − 3.26 (− 6.43 to − 0.10) | < 0.05 |
  Past prednisone | 1.33 (− 5.11 to 2.45) | 0.489 | − 1.32 (− 5.10 to 2.46) | 0.493 | − 1.22 (− 4.99 to 2.55) | 0.526 |
Number of comorbid conditions | 0.10 (− 0.63 to 0.82) | 0.795 | 0.08 (− 0.65 to 0.81) | 0.826 | 0.90 (− 0.08 to 1.88) | 0.071 |
Social support and Active lifestyle | ||||||
 Tangible support | −0.03 (− 0.10 to 0.05) | 0.458 | − 0.03 (− 0.10 to 0.04) | 0.432 | − 0.03 (− 0.10 to 0.04) | 0.446 |
 Affectionate support | 0.09 (− 0.03 to 0.22) | 0.134 | 0.10 (− 0.03 to 0.22) | 0.121 | 0.10 (− 0.02 to 0.23) | 0.099 |
 Positive social interaction | 0.02 (− 0.09 to 0.14) | 0.675 | 0.02 (− 0.09 to 0.13) | 0.731 | 0.02 (− 0.09 to 0.13) | 0.739 |
 Emotional/information support | 0.00 (−0.09 to 0.10) | 0.956 | 0.01 (−0.09 to 0.10) | 0.899 | 0.00 (−0.10 to 0.10) | 0.990 |
 Active lifestyle | 0.28 (0.16 to 0.40) | < 0.001 | 0.28 (0.16 to 0.40) | < 0.001 | 0.28 (0.16 to 0.40) | < 0.001 |
MG-ADL | − 4.02 (− 4.37 to − 3.67) | < 0.001 | − 4.02 (− 4.36 to − 3.67) | < 0.001 | − 3.99 (− 4.34 to − 3.64) | < 0.001 |
Gender (0 = male; 1 = female) |  |  | − 0.89 (− 3.74 to 1.97) | 0.542 | 0.90 (− 2.29 to 4.09) | 0.579 |
Gender × Comorbiditiesa |  |  |  |  | −1.71 (− 3.08 to − 0.34) | < 0.05 |
Adjusted R-squared | 0.6155 | 0.6152 | 0.6177 | |||