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Table 3 Comparison of change between the HIT group and the MICT group from baseline to follow-up

From: High-intensity interval training and health-related quality of life in de novo heart transplant recipients – results from a randomized controlled trial

Variables

Change within the HIT group

Mean ± SD

(n = 37)

Change within the MICT group

Mean ± SD

(n = 41)

Difference in mean change between groups

mean [95% CI]

P value Difference in change between groups

Health-related quality of life SF-36v2 components summaries and subscales

 Physical Component Summary (PCS)

6.3 ± 8.2**

5.7 ± 5.7**

0.6 [− 3.1, 4.2]

0.762

 Mental Component Summary (MCS)

0.9 ± 12.5

− 2.6 ± 9.3

3.4 [− 1.5, 8.5]

0.170

 Physical Functioning

5.8 ± 5.6**

5.2 ± 5.6**

0.6 [− 2.0, 3.2]

0.653

 Role Physical

10.5 ± 11.2**

6.2 ± 10.0**

4.3 [− 0.6, 9.1]

0.082

 Bodily Pain

2.7 ± 11.5

1.0 ± 11.4

1.7 [− 3.5, 6.9]

0.509

 General Health

2.6 ± 8.3

1.4 ± 8.6

1.1 [− 2.7, 4.9]

0.555

 Vitality

2.0 ± 9.2

2.6 ± 7.3*

− 0.6 [− 4.3, 3.2]

0.760

 Social Functioning

3.6 ± 10.5*

2.0 ± 11.6

1.5 [− 3.5, 6.5]

0.541

 Role Emotional

5.2 ± 13.4*

− 2.0 ± 11

7.2 [1.6, 12.8]

0.012

 Mental Health

0.6 ± 9.0

− 1.4 ± 7.3

2.0 [− 1.7, 5.7]

0.284

 HADS Anxiety

−1.0a

−0.8a

 

0.920c

 HADS Depression

−1.0b

−0.2a

 

0.427c

Cardiopulmonary exercise test

 VO2peak (mL/kg/min)

4.8 ± 4.1**

3.1 ± 3.5**

1.8 [0.1, 3.5]

0.044

 Improvement in mL/kg/min (%)

25.2 ± 21.1**

15.1 ± 17.8**

10.1 [1.3, 19.0]

0.025

 % of predicted VO2peak

13.2 ± 10.7**

8.5 ± 9.1**

4.7 [0.2, 9.2]

0.040

 RPE (Borg scale score)

0.1 ± 0.8

0.3 ± 1.2

0.2 [−0.3, 0.7]

0.424

 RER

0.02 ± 0.1

−0.01 ± 0.1

0.02 [− 0.03, 0.1]

0.338

Muscular capacity

 Maximal muscle strength extensors (Newton meter)

54 ± 49**

36 ± 34**

178 [− 3, 39]

0.094

 Muscular exercise capacity extensors (Joule)

1016 ± 812**

551 ± 780**

464 [63, 863]

0.024

  1. Health-related quality of life, exercise capacity and muscular strength at baseline (~ 11 weeks after HTx and at 9 months intervention (first yearly annual follow-up). Variables are presented as mean ± standard deviation. CI Confidence Interval, HADS Hospital Anxiety and Depression Scale, HIT High-intensity interval training, MICT moderate intensity contionuous training, SD standard deviation, RER Respiratory exchange ratio, RPE Rated perceived exertion, VAS visual analogue scale
  2. Within group: **p < 0.001, *p < 0.05
  3. aBased on negative ranks
  4. bBased on positive ranks
  5. cMann-Whitney U test
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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