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Table 2 Baseline and follow-up results in the HIT group and the MICT groupd

From: High-intensity interval training and health-related quality of life in de novo heart transplant recipients – results from a randomized controlled trial

Variables

Baseline

Follow-up

HIT

(n = 37)

t-test, P value

Baseline

Follow-up

MICT

(n = 41)

t-test, P value

Health-related quality of life SF-36v2 components summaries and subscales

 Physical Component Summary (PCS)

42.2 ± 7.6

48.4 ± 9.3

<  0.001

43.2 ± 7.7

49.0 ± 8.4

< 0.001

 Mental Component Summary (MCS)

52.5 ± 12.9

53.4 ± 11.9

0.673

55.1 ± 8.2

52.5 ± 9.6

0.086

 Physical Functioning

45.0 ± 7.0

50.8 ± 6.0

< 0.001

46.4 ± 6.4

51.6 ± 6.6

< 0.001

 Role Physical

37.6 ± 10.4

48.1 ± 9.3

< 0.001

40.8 ± 10.0

47.0 ± 10.0

< 0.001

 Bodily Pain

47.8 ± 9.3

50.5 ± 10.5

0.163

48.1 ± 9.2

49.1 ± 12.2

0.583

 General Health

48.2 ± 9.4

50.8 ± 11.0

0.067

49.8 ± 7.3

51.2 ± 9.4

0.292

 Vitality

50.6 ± 10.8

52.6 ± 12.7

0.196

51.2 ± 9.4

53.6 ± 9.0

0.031

 Social Functioning

46.7 ± 9.9

50.2 ± 9.1

0.047

48.7 ± 8.7

50.7 ± 9.0

0.278

 Role Emotional

46.8 ± 13.1

52.0 ± 9.1

0.027

50.7 ± 7.7

48.7 ± 10.5

0.246

 Mental Health

53.1 ± 11.0

53.7 ± 9.7

0.684

55.4 ± 7.8

54.0 ± 9.7

0.232

 HADS Anxiety median (IR)

3.0 (3.5)

2.0 (4.5)

0.310a

3.0 (3.5)

3.0 (4)

0.400a

 HADS Depression median (IR)

2.0 (3.5)

2.0 (4.8)

0.331a

1.0 (2.5)

1.0 (3.8)

0.866a

 VAS scale (0–100) median (IR)b

 

82.0 (20.5)

  

75.5 (37.3)

0.235c

Cardiopulmonary exercise test

 VO2peak (mL/kg/min)

19.5 ± 4.3

24.4 ± 6.5

< 0.001

21.3 ± 5.3

24.4 ± 6.7

< 0.001

 % of predicted VO2peak

53.3 ± 11.6

66.6 ± 15.4

< 0.001

58.4 ± 12.5

66.9 ± 14.8

< 0.001

 RPE (Borg scale score)

18.7 ± 0.5

18.8 ± 0.6

0.290

18.5 ± 1.1

18.8 ± 0.7

0.098

 RER

1.17 ± 0.11

1.19 ± 0.1

0.314

1.22 ± 0.13

1.22 ± 0.1

0.751

Muscular capacity

 Maximal muscle strength extensors (Newton meter)

184 ± 74

237 ± 81

< 0.001

186 ± 73

222 ± 80

< 0.001

 Muscular exercise capacity extensors (Joule)

2154 ± 952

3170 ± 1267

< 0.001

2319 ± 1201

2870 ± 1240

< 0.001

  1. Health-related quality of life, exercise capacity and muscular strength at baseline (~ 11 weeks after HTx and at 9 months intervention (first yearly annual follow-up). Variables are presented as mean ± standard deviation or median (Interquartile range (IR)).HADS Hospital Anxiety and Depression Scale, HIT High-intensity interval training, MICT moderate intensity contionuous training, RER Respiratory exchange ratio, RPE Rated perceived exertion, VAS visual analogue scale
  2. aWilcoxon Signed Rank Test
  3. bMeasured at follow-up only
  4. cMann-Whitney U test (difference between groups at follow-up)
  5. dNo difference between groups at baseline