Association between diabetes mellitus and health-related quality of life among patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

Table 2 The linear regression between DM and KDQOL™-36 scales

Regression coefficient	Log transformed symptoms and problems (S)^**		Effects of kidney disease (E)		Burden of kidney disease (B)		SF-12 Physical Function (PCS)		SF-12 Mental Function (MCS)
Regression coefficient	univariate regression	multivariable regression^a	univariate regression	multivariable regression^b	univariate regression	multivariable regression^c	univariate regression	multivariable regression^d	univariate regression	multivariable regression^e
Age (year)	0.0018^*	0.0008^*	− 0.071^*	− 0.027	0.042		−0.15^*	− 0.084^*	− 0.0023
Sex	−0.024^*	− 0.022^*	1.06^*	0.86	5.54^*	4.08^*	1.55^*	1.46^*	0.81^*	0.64
Marriage	0.0084		0.44		1.52		0.39		−0.29
Race	−0.0011		−0.96		2.90		−0.72		1.10
Education	−0.032^*	−0.010^*	1.13^*	−0.60	6.20^*	2.32	2.12^*	0.50	0.83^*	0.10
Treatment period	0.029^*	0.015^*	−1.56^*	−0.70	−2.36^*	− 1.05	− 1.76^*	− 0.80^*	− 0.14
Smoking	− 0.0021		− 0.033		2.33^*	0.49	−0.13		0.22
Economic burden	0.045^*	0.036^*	−4.75^*	−4.67^*	−21.39^*	−19.08^*	− 4.48^*	− 3.88^*	− 3.12^*	− 2.68^*
BMI (kg/m²)	−0.00073		0.19^*	0.20^*	0.52^*	0.39	0.064		0.17^*	0.15^*
FPG (mmol/L)	0.0089^*		−0.66^*		−0.93^*		−0.78^*		−0.059
eGFR (ml/min/1.73 m²)	−0.00068^*	−0.0003^*	0.041^*	0.021^*	0.085^*	0.048^*	0.061^*	0.026^*	0.021^*	0.012^*
CVD	0.057^*	0.040^*	−2.93^*	−2.36^*	−2.25		−5.29^*	−3.60^*	−1.65^*	−1.66^*
DM	0.030^*	0.010^*	− 1.39^*	−0.81	− 1.89^*	− 1.08	−4.04^*	−2.18^*	− 0.22^*	− 0.078
Log (ACR (mg/g))	0.0043^*	0.0034^*	−0.37^*	− 0.31^*	− 1.72^*	− 1.12^*	− 0.37^*	−0.29^*	− 0.35^*	−0.30^*

Note 1: ^* Statistically significant at 0.05
Note 2: ^** The log transformation was performed by the formula: ln (175-score of symptoms and problems)
Note 3: a Adjusted for age, sex, education, treatment period, economic burden, eGFR, CVD and Log (ACR)
Note 4: b Adjusted for age, sex, education, treatment period, economic burden, BMI, eGFR, CVD and Log (ACR)
Note 5: c Adjusted for sex, education, treatment period, smoking, economic burden, BMI, eGFR and Log (ACR)
Note 6: d Adjusted for age, sex, education, treatment period, economic burden, eGFR, CVD and Log (ACR)
Note 7: e Adjusted for sex, education, economic burden, BMI, eGFR, CVD and Log (ACR)

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