Table 5 Characteristics, assessment, and results of structural validity papers in DMD samples for measures included in the review
PROM | Reference | Country (language) | Patient characteristics | COSMIN Quality Rating | Analysis – model | Results (summary) | |||
|---|---|---|---|---|---|---|---|---|---|
N | Age (yr, M ± SD) | % ambulatory | PROM score | ||||||
PedsQL 4.0 GCS | Lim et al. 2014 [72] | USA (English) | 63 boys with DMD (and up to 50 parents, not necessarily matched) | 10.2 ± 2.5 | 95.24 | Child: M = 64.5, SD = 15.3. Parent: M = 56.2, SD = 12.9. | Doubtful | Rasch (model not specified) | Model misfit for items determined with infit > 1.4 and outfit > 2.0 MnSq values and standardized scores > 2.0. All items fit in parent proxy-reports of physical health scale and child self-reports of psychosocial health scale. 2 out of 8 items showed high infit statistics in child self-reports of the physical health scale (taking a bath or shower; doing chores around the house). In addition 2 out of 15 items showed high infit for the parent proxy-reports of the psychosocial health scale (trouble sleeping; keep up with school work). |
PedsQL 3.0 NMM | Landfeldt et al. 2018 [66] | UK / USA (English) | 278 (95 UK) | 16 ± 7 | 40% not “full-time wheelchair dependent” | Not reported | Very good | Rasch PCM | Eight items displayed inadequate fit (χ2: p > 0.01). Six items had fit residuals ≤ −2.5 or ≥ 2.5 (4 significant at p < .05). Inadequate overall fit (χ2 item-trait interaction: p = < .001). Disordered thresholds for 22 of 25 items. Suboptimal targeting. |