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Table 1 Patient characteristics, patient-reported outcomes and exercise test outcomes at baseline

From: Association between patient-reported outcomes and exercise test outcomes in patients with COPD before and after pulmonary rehabilitation

 

Whole group

n

Completers

n

Non-completers

n

N = 518

 

N = 419

 

N = 99

 

Patient characteristics

 Gender, male (%)

288 (55.6)

518

232 (55.4)

419

56 (56.6)

99

 Age, years

64.1 ± 9.1

518

64.3 ± 8.8

419

63.2 ± 10.3

99

 Current smoker, n (%)

114 (22.1)

518

79 (18.9)

419

35 (35.4)*

98

 Pack years, n

40.0 (30.0–50.0)

518

40.0 (30.0–50.0)

403

40.0 (30.0–51.0)

93

 BMI, kg/m2

26.2 ± 5.8

518

26.2 ± 5.7

419

26.2 ± 6.3

99

 FFMI, kg/m2

17.0 ± 2.5

499

17.0 ± 2.4

405

17.0 ± 2.6

94

 FEV1, L

1.29 ± 0.60

518

1.30 ± 0.60

419

1.26 ± 0.60

99

 FEV1% predicted

48.6 ± 20.0

518

48.9 ± 20.0

419

47.3 ± 20.1

99

 FEV1 / FVC, %

37.5 ± 12.2

518

37.3 ± 12.1

419

38.4 ± 12.9

99

 mMRC-score (0/1/2/3/4), %

2/17/38/25/18

512

2/17/40/22/18

414

0/15/27/36/22

98

 GOLD classification (I/II/III/IV), %

7/36/37/20

518

8/36/35/21

419

6/33/43/17

99

 GOLD classification (A/B/C/D), %

3/20/5/72

518

2/22/5/71

419

5/12/5/78

99

Oxygen saturation, %

94.6 (92.7–96.0)

510

94.6 (92.8–96.0)

414

94.0 (92.0–96.0)

96

 LTOT, n (%)

125 (24.1)

518

104 (24.8)

419

21 (21.2)

96

Patient-reported outcomes

 mMRC score, points

2.4 ± 1.0

512

2.4 ± 1.0

414

2.7 ± 1.0

98

 SGRQ-C total score, points

61.1 ± 17.4

504

60.1 ± 17.1

409

65.4 ± 18.1*

95

 CAT total score, points

21.5 ± 6.6

505

21.5 ± 6.6

410

21.7 ± 6.9

95

 CCQ total score, points

2.6 ± 1.0

502

2.6 ± 1.0

409

2.8 ± 1.1

93

 HADS-A score, points

7.8 ± 4.5

500

7.5 ± 4.4

407

9.0 ± 4.9*

93

 HADS-D score, points

7.5 ± 4.3

500

7.4 ± 4.2

407

8.0 ± 4.9

93

 CDS total score, points

72.0 (68.0–75.0)

480

69.7 ± 7.2

389

68.4 ± 7.9

91

Exercise test outcomes

 6MWD, meters

424 ± 124

513

431 ± 124

417

393 ± 123*

96

 CPET Wmax, W

70.1 ± 34.2

493

70.9 ± 33.7

407

66.6 ± 36.7

86

 CPET VO2peak, ml/min

1090 ± 414

390

1094 ± 407

316

1071 ± 446

74

 CWRT endurance time, seconds

224 (169–327)

477

235 (174–338)

392

199 (149–294)*

85

 TUG test time, seconds

9.8 (8.5–11.8)

500

9.6 (8.3–11.6)

408

10.2 (8.7–12.7)

92

 Quadriceps peak torque, Nm

94.1 ± 36.4

466

94.4 ± 35.9

383

93.5 ± 39.1

83

 Quadriceps total work, J

1627 ± 741

465

1641 ± 724

382

1559 ± 815

83

  1. Summary variables are presented as n (%) for discrete variables, mean ± standard deviation for quantitative variables or median (Interquartile range) for skewed variables, * p<0.01. ‘n’ represents the total number of sample values per analysis
  2. Abbreviations: BMI body mass index, FFMI Fat Free Mass Index, FEV1 forced expiratory volume in the first second, FVC forced vital capacity, mMRC modified Medical Research Council scale, GOLD Global Initiative for Chronic Obstructive Lung Disease, LTOT Long Term Oxygen Therapy, mMRC modified Medical Research Council scale, SGRQ-C COPD-specific St. George Respiratory Questionnaire score, CAT COPD Assessment Test, CCQ Clinical COPD Questionnaire, HADS-A Hospital Anxiety and Depression Scale, Anxiety subscale, HADS-D Hospital Anxiety and Depression Scale, Depression subscale, CDS Care Dependency Scale, 6MWD 6-min walking distance, CPET Cardiopulmonary Exercise Test, Wmax maximal achieved workload, W Watts, VO2peak peak oxygen uptake, ml = milliliter min = minute, CWRT Constant Work-Rate Test, TUG Timed ‘Up and Go’, Nm Newtonmeter, J Joules