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Table 9 Effect of utility mapping on the incremental cost/QALY in a discrete event simulation model

From: Evaluation of the performance of algorithms mapping EORTC QLQ-C30 onto the EQ-5D index in a metastatic colorectal cancer cost-effectiveness model

 

Utility

Observation

Utility

CB Maintenance

Incremental costs (€)

Incremental QALYs

ICER (€/QALY)

ICER difference

EQ-5D-3L based utility

0.829 (SE 0.0080)

0.839 (SE 0.0055)

30,163

0.179

168,048

 

Versteegh utility (6)

0.876 (SE 0.0052)

0.875 (SE 0.0040)

30,163

0.191

157,908

- €10,140

Longworth (Dutch) utility(7)

0.840 (SE 0.0052)

0.843 (SE 0.0038)

30,163

0.178

169,812

€1765

Model 1a

0.836 (SE 0.0053)

0.837 (SE 0.0041)

30,163

0.174

173,141

€5094

  1. CB Capecitabine and bevacizumab
  2. abased on the OLS domain scores