Evaluation of the performance of algorithms mapping EORTC QLQ-C30 onto the EQ-5D index in a metastatic colorectal cancer cost-effectiveness model

Franken, Mira D.; de Hond, Anne; Degeling, Koen; Punt, Cornelis J. A.; Koopman, Miriam; Uyl-de Groot, Carin A.; Versteegh, Matthijs M.; van Oijen, Martijn G. H.

doi:10.1186/s12955-020-01481-2

Table 5 Regression results for model 3: EQ-5D-3L based utilities on QLQ-C30 questions as dummy variables

From: Evaluation of the performance of algorithms mapping EORTC QLQ-C30 onto the EQ-5D index in a metastatic colorectal cancer cost-effectiveness model

Variable	Coefficient (SD)	t-value	p-value	95% CI
Constant	0.966 (0.006)	158.046	< 0.001	[0.954, 0.978]
QLQ1_quite a bit	− 0.020 (0.009)	−2.142	0.032	[− 0.038, − 0.002]
QLQ2_a little	− 0.014 (0.006)	− 2.324	0.020	[− 0.026, − 0.002]
QLQ3_a little	− 0.028 (0.008)	− 3.670	< 0.001	[− 0.043, − 0.013]
QLQ3_quite a bit	− 0.046 (0.014)	−3.231	0.001	[− 0.074, − 0.018]
QLQ5_ a little	−0.065 (0.013)	−4.903	< 0.001	[− 0.091, − 0.039]
QLQ5_ quite a bit	− 0.225 (0.037)	−6.097	< 0.001	[− 0.297, − 0.153]
QLQ6_ a little	− 0.047 (0.007)	− 6.978	< 0.001	[− 0.06, − 0.034]
QLQ6_ quite a bit	−0.076 (0.011)	−6.780	< 0.001	[− 0.098, − 0.054]
QLQ6_ very much	− 0.259 (0.020)	− 13.215	< 0.001	[− 0.297, − 0.22]
QLQ9_ a little	−0.068 (0.007)	−10.468	< 0.001	[− 0.081, − 0.055]
QLQ9_quite a bit	− 0.099 (0.012)	− 8.327	< 0.001	[− 0.123, − 0.076]
QLQ9_very much	−0.168 (0.023)	−7.383	< 0.001	[− 0.213, − 0.123]
QLQ18_very much	− 0.058 (0.020)	− 2.933	0.003	[− 0.097, − 0.019]
QLQ19_quite a bit	−0.062 (0.014)	− 4.475	< 0.001	[− 0.089, − 0.035]
QLQ22_a little	− 0.027 (0.006)	− 4.251	< 0.001	[− 0.039, − 0.014]
QLQ22_quite a bit	− 0.046 (0.012)	− 3.733	< 0.001	[− 0.07, − 0.022]
QLQ23_quite a bit	− 0.060 (0.018)	− 3.294	0.001	[− 0.096, − 0.024]
QLQ23_ very much	−0.211 (0.049)	−4.338	< 0.001	[− 0.306, − 0.115]
QLQ24_a little	− 0.045 (0.007)	− 6.117	< 0.001	[− 0.059, − 0.03]
QLQ24_quite a bit	−0.108 (0.020)	−5.264	< 0.001	[− 0.148, − 0.068]
QLQ24_very much	− 0.213 (0.035)	− 6.039	< 0.001	[− 0.283, − 0.144]
QLQ26_a little	−0.033 (0.007)	−4.874	< 0.001	[− 0.047, − 0.02]
QLQ26_quite a bit	− 0.068 (0.016)	− 4.385	< 0.001	[− 0.099, − 0.038]
QLQ28_ very much	−0.056 (0.022)	−2.603	0.009	[− 0.098, − 0.014]

p-values result from a t-test

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