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Table 1 Baseline characteristics of patients on somatostatin analogue treatment for metastatic disease from small-intestinal neuroendocrine tumour

From: Patient reported symptoms, coping and quality of life during somatostatin analogue treatment for metastatic small- intestinal neuroendocrine tumours

 

Baseline N = 88

1-year follow-up N = 77

Males,n(%)

47 (53.4%)

 

Age, median (range)

65.0 (32–87) years

 

Time since diagnosis, median (range)

4.82 (0.3–34.3) years

 

Time since first treatment, median (range)

3.09 (0.2–15.3) years

 

Weight, median (range)

72.5 (40–130) kg

70.0 (40–132) kg

Weight change from baseline, median (range)

 

0.0 (−15–13) kg

Weight loss in the last year,n(%)

None

61 (69.3%)

51 (67.1%)b

0–5%

18 (20.5%)

17 (22.4%)b

6–10%

7 (8.0%)

6 (7.9%)b

> 10%

2 (2.3%)

2 (2.6%)b

Occupation,n(%)

Retired

53 (60.2%)

50 (66.7%)b

Non-retired

35 (39.8%)

25 (33.3%)b

Working (% of non-retired)

15 (42.9%)

12 (48.0%)b

Not working (% of non-retired)

20 (57.1%)

13 (52.0%)b

Disease status,n(%)

Metastatic mesenteric lymph nodes

34 (38.6%)

 

Other metastatic lymph nodes

35 (39.8%)

 

Liver metastases

78 (88.8%)

 

Lung metastases

1 (1.1%)

 

Other metastases

23 (26.1%)

 

Surgery of primary tumour,n(%)

74 (84.1%)

 

Surgery of mesenteric lymph nodes

42 (49.4%)b

 

Surgery of liver metastases

14 (17.1%)b

 

Ki67, median (min-max)

1.0% (1–15%)

 

Ki67, categorised

0–2%

60 (68.2%)

 

> 2%

28 (31.8%)

 

Performance status,n(%)

0

49 (55.7%)

48 (62.3%)

1

31 (35.2%)

16 (20.8%)

2

7 (8.0%)

11 (14.3%)

3

1 (1.1%)

2 (2.6%)

Smoker,n(%)

11 (12.6%)b

 

Prior treatments

Interferon

22 (25.0%)

4 (5.2%)c

PRRT

21 (23.9%)

19 (24.7%)c

5-HIAA in urine, above normal,n(%)

42 (79.2%)b

25 (83.3%)b

CgA in blood, above normal,n(%)

64 (72.7%)

55 (75.3%)b

Pancreatic enzyme supplement,n(%)

Current use

26 (29.5%)

27 (35.5%)b

Prior and current use

39 (44.3%)

NA

Loperamide,n(%)

Current use

20 (22.7%)

17 (22.4%)b

Prior and current use

38 (43.2%)

NA

Cholestyramine,n(%)

Current use

6 (6.8%)

6 (7.9%)b

Prior and current use

13 (14.8%)

NA

Vitamin supplements,n(%)

Current use

59 (67.0%)

64 (83.1%)

  1. 5-HIAA 5-hydroxyindoleacetic acid, CgA Chromogranin A, ECOG Eastern Cooperative Oncology Group, PRRT peptide receptor radionuclide therapy