Health-related quality of life among children with transfusion-dependent thalassemia: A cross-sectional study in Malaysia

Table 4 Multiple linear regression analysis predictors of PedsQL™ subscales

PedsQL™ Subscale	β coefficient	95% Confidence interval
Total Summary Score (TSS)		81.74	90.62
Age 5–7.9 years	−4.362	−9.967	1.242
Age 8–12.9 years	−5.422	−10.436	− 0.409
Age 13–18.9 years	−6.045	−11.206	− 0.884
Dual Therapy	−6.594	−10.5	−2.689
Constant = 86.18, R² = 0.057, F (4, 359) = 5.40, p < 0.001
Physical Health Summary Score (PHSS)		86.85	101.50
Age 5–7.9 years	− 10.344	−17.076	−3.611
Age 8–12.9 years	−12.515	−18.567	− 6.462
Age 13–18.9 years	−15.883	−22.800	−8.967
Male	4.543	1.149	7.938
Parent Proxy-reported	−2.879	−7.805	2.048
Constant = 94.18, R² = 0.075, F (5, 358) = 5.80,p < 0.001
Psychosocial Health Summary Score (PCHS)		79.111	82.398
Dual Therapy	−7.997	−11.979	−4.015
Constant = 80.76, R² = 0.041, F (1, 362) = 15.60, p < 0.001

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