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Table 1 Demographic and clinical characteristics of study population

From: Health-related quality of life among children with transfusion-dependent thalassemia: A cross-sectional study in Malaysia

Characteristics N (%)
Age (years) (n = 368)
 2–4.9 years old 36 (9.78)
 5–7.9 years old 62 (16.85)
 8–12.9 years old 134 (36.41)
 13–18.9 years old 136 (36.96)
Gender (n = 368)
 Male 178 (48.37)
 Female 190 (51.63)
Ethnicity (n = 368)
 Malay 242 (65.85)
 Chinese 44 (11.92)
 Kadazan-Dusun 55 (14.91)
 Others 27 (7.32)
Region (n = 368)
 Northern (Penang, Perak) 43 (11.68)
 Central (Selangor, Federal Territory of Kuala Lumpur, Negeri Sembilan) 76 (20.65)
 Southern (Johore) 45 (12.23)
 East Coast (Pahang, Kelantan, Terengganu) 104 (28.26)
 East Malaysia (Sabah, Sarawak) 100 (27.17)
Education Level of Parents who completed Proxy-Report (n = 257)
 No Formal Education 12 (4.67)
 Primary or Secondary School 183 (71.20)
 Tertiary Education 62 (24.12)
Education Level of Children who completed Self-Report (n = 111)
 No Formal Education 3 (2.70)
 Primary or Secondary School 97 (87.39)
 Tertiary Education 11 (9.91)
Source of survey (n = 368)
 Self-reported 111 (30.16)
 Parent Proxy-reported 257 (69.84)
Presence of Iron Overload Complication (n = 368)
 Absent 267 (72.56)
 Present 101 (27.44)
 Endocrine Only 57 (15.49)
 Liver Only 24 (6.52)
 Cardiac Only 3 (0.82)
 Multi-system 20 (5.43)
Iron Chelation Therapy Route of Administration (n = 368)
 Subcutaneous Injection (SC) 42 (11.41)
 Oral (PO) 268 (72.83)
 Subcutaneous Injection (SC) + Oral (PO) 58 (15.76)
Iron Chelation Therapy (n = 368)
 SC Desferrioxamine 42 (11.41)
 PO Deferasirox 233 (63.32)
 PO Deferiprone 29 (7.88)
 SC Desferrioxamine + PO Deferiprone 41 (11.14)
 SC Desferrioxamine + PO Deferasirox 17 (4.62)
 PO Deferiprone + PO Deferasirox 6 (1.63)
Number of iron chelating agents (n = 368)
 Monotherapy 304 (82.61)
 Dual Therapy 64 (17.39)
History of Serious Adverse Event with Iron Chelation Therapy(n = 368)
 No 345 (93.75)
 Yes 23 (6.25)
Characteristics (N = 368) Mean (SD)
Age (years) 10.59 (4.37)
Age at first transfusion (years) 2.66 (3.01)
Number of years receiving blood transfusion 7.68 (4.66)
  1. N number, SD standard deviation