Validation of the Chinese EORTC chronic lymphocytic leukaemia module – application of classical test theory and item response theory

Table 4 Known-groups validity between patients receiving treatment and not receiving treatment

	Treatment (n = 228)		No treatment (n = 49)		Difference (95% C.I.)	p-value
	Mean	sd	Mean	sd	Difference (95% C.I.)	p-value
SB (item 1–6)	31.75	17.41	20.41	14.98	11.34 (6.5 ~ 16.17)	< 0.001
PC (item 7–10)	31.91	20.02	24.32	15.2	7.59 (2.53 ~ 12.64)	0.003
WF (item 11–17)	57.56	27.14	52.84	24.97	4.72 (−3.23~12.68)	0.24

There are four kinds of treatment: chemotherapy, radiation therapy, immunotherapy, or surgery
95% C.I., 95% confidence interval
p-value was calculated based on the robust one-way ANOVA on trimmed means suggested by Wilcox
SB symptom burden, PC physical condition/fatigue, WF Worries/fears about health and functioning

ISSN: 1477-7525