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Table 5 Results of a multivariate multilevel model for QOL domain scores

From: Multivariate multilevel modeling of quality of life dynamics of HIV infected patients

EffectsPhysical HealthPsychological ScoreLevel of IndependenceSocial Relationship
Intercepts10.8 (7.43, 14.2)**9.63 (6.28, 12.9)**12.8 (8.7, 16.98)**13.5 (9.9, 17.16)*
Time0.18 (0.01, 0.37)**0.21 (0.04, 0.38)**0.05(− 0.27, 0.18)0.03(− 0.19, 0.14)
Thrombocytopenia: Yes0.67(− 0.56, 1.89)0.52(− 0.69, 1.73)− 2.01(−3.89, − 0.13)*− 0.33(−1.93, 1.27)
TB: No0.38 (0.02, 0.74)**0.01(− 0.35, 0.38)0.16(− 0.48, 0.80)0.05(− 0.47, 0.56)
Anemia: No1.38 (1.17, 2.12)*− 0.61(− 1.37, 0.15)−0.58(− 1.35, 0.18)0.06(− 0.96, 1.09)
Adverse Event: Normal3.33 (2.11, 4.55)***1.43 (1.23, 3.18)*1.64 (0.42, 2.87)1.64 (1.02, 2.87)*
Adverse Event: Mild2.86 (1.66, 4.06)*1.23 (1.03, 2.43)***−0.08(− 1.98, 1.82)1.44 (0.18, 3.06)
Adverse Event: Advanced3.34 (2.16, 4.53)*1.32 (0.14, 2.51)− 0.76(− 2.65, 1.13)0.86(− 0.76, 2.47)
Education: Grade 9–100.60 (0.26, 0.88)0.25(− 0.60, 1.09)0.53(− 0.41, 1.48)0.65(− 0.20, 1.50)
Education:> Grade 11 Grade0.22 (0.01, 0.99)*1.26 (1.18, 2.89)**0.54(− 0.79, 1.86)0.20(− 0.99, 1.39)
Marital Status: Single/no sexual partner0.20(−1.43, 1.83)1.25 (0.38, 2.89)− 0.67(− 2.45, 1.11)− 0.51(− 2.10, 1.07)
Marital Status: Married (stable sexual partner)0.13(−1.69, 1.94)2.14 (1.01, 3.87)*−1.36(− 3.34, 0.62)−1.10(− 2.87, 0.67)
Age: 21–39 years− 0.34(− 1.16, − 0.49)*0.26(− 0.59, 1.12)−1.89(− 2.97, − 0.81)*−1.25(− 2.19, − 0.30)*
Age: 40–59 years0.26(− 1.30, 1.81)0.79(− 0.82, 2.39)−1.49(− 3.48, 0.49)− 0.09(− 1.84, 1.66)
Sex while drunk: Yes−0.08(− 0.99, 0.82)0.22(− 0.72, 1.16)0.03(− 1.18, 1.24)− 0.49(− 1.55, 0.57)
Weight0.01 (0.001, 0.03)*0.01 (0.002, 0.03)*0.01(− 0.01, 0.03)− 0.01(− 0.02, 0.01)
Viral Load−0.21(− 0.39, − 0.03)−0.29(− 0.46, − 0.10)*−0.09(− 0.37, − 0.01)*−0.06(− 0.30, − 0.01)*
RBC indices0.15(− 0.09, 0.38)0.28 (0.04, 0.51)*− 0.22(− 0.56, 0.13)0.04(− 0.25, 0.34)
Hb and haematocrit component−0.04(− 0.26, 0.18)−0.11(− 0.33, 0.12)−0.18(− 0.51, 0.15)0.05(− 0.24, 0.33)
Granulocytes component−0.05(− 0.23, 0.13)0.06(− 0.12, 0.25)− 0.06(− 0.33, 0.21)0.14(− 0.09, 0.37)
Mononuclear component0.28 (0.09, 0.48)*− 0.13(− 0.30, 0.05)0.21(− 0.05, 0.47)0.10(− 0.12, 0.32)
Eosinophil component− 0.04(− 0.12, 0.03)− 0.07(− 0.15, 0.00)−0.12(− 0.24, 0.01)0.04(− 0.07, 0.15)
Liver enzymes abnormality component−0.08(− 0.04, − 0.08)*−0.18(− 0.43, − 0.09)*0.14(−0.12, 0.40)−0.15(− 0.37, 0.07)
Electrolyte component−0.06(− 0.22, 0.10)−0.18(− 0.34, 0.02)0.28 (0.02, 0.53)*−0.10(− 0.32, 0.11)
Time Slope
 Thrombocytopenia: Yes−0.03(− 0.08, 0.01)−0.02(− 0.06, 0.02)0.16 (− 0.23,-0.08)*0.02(− 0.04, 0.08)
 Viral Load−0.06(− 0.1, − 0.001)**−0.01(− 0.09, − 0.002)*−0.001(− 0.01, 0.01)−0.001(− 0.01, 0.01)
 Electrolyte component0.01 (0.001, 0.02)*0.04 (0.01, 0.06)*0.00(− 0.01, 0.01)0.00 (0.00, 0.01)
 RBC indices0.00(−0.01, 0.01)−0.01(− 0.02, 0.00)0.01 (0.00, 0.03)0.00(− 0.01, 0.01)
 Hb and haematocrit component0.06 (0.01, 0.09)*0.02 (0.01, 0.03)*0.02 (0.01, 0.03)*0.01 (0.001, 0.02)*
 Granulocytes component0.00 (0.00, 0.01)0.00(− 0.01, 0.00)0.01 (0.00, 0.02)0.00(− 0.01, 0.01)
 Mononuclear component0.001(− 0.01, 0.01)− 0.01(− 0.02, 0.001)0.02 (0.01, 0.02)*0.001(− 0.01, 0.002)
 Liver enzymes abnormality component− 0.01(− 0.02, −  0.001)*−0.01(− 0.02, 0.001)−0.01(− 0.02, 0.002)−0.01(− 0.02, 0.001)
 Weight0.01 (0.001, 0.02)*0.01 (0.001, 0.02)*0.001(− 0.01, 0.01)0.001(− 0.01, 0.01)
 Adverse Event: Normal0.03 (0.01, 0.05)**− 0.03(− 0.11, 0.04)0.09 (0.01, 0.17)**−0.04(− 0.12, 0.04)
 Adverse Event: Mild0.01 (0.008, 0.06)**−0.03(− 0.11, 0.04)0.06 (0.03, 0.12)**−0.04(− 0.12, 0.04)
 Adverse Event: Advanced−0.04(− 0.12, 0.03)−0.04(− 0.11, 0.04)0.08 (0.00, 0.16)**−0.02(− 0.10, 0.06)
 Anemia: No0.03 (0.001, 0.07)**0.02(− 0.01, 0.06)−0.06(− 0.11, 0.01)0.001(− 0.04, 0.04)
 Education: Grade 9–100.001(− 0.02, 0.02)0.001(− 0.02, 0.02)0.04 (0.01, 0.08)***−0.02(− 0.04, 0.00)
 Education:> Grade 11−0.01(− 0.04, 0.03)0.01(− 0.02, 0.04)0.03 (0.01, 0.09)*0.01(− 0.03, 0.04)
 Marital Status: Single0.01(− 0.02, 0.04)0.00(− 0.04, 0.03)−0.02(− 0.06, 0.01)0.03(− 0.01, 0.07)
 Marital Status: Married (stable sexual partner)−0.01(− 0.05, 0.03)−0.02(− 0.06, 0.02)−0.01(− 0.06, 0.03)0.05 (0.01, 0.10)**
 Age: 21–39 years0.02 (0.01, 0.04)*0.00(−0.03, 0.04)0.07 (0.03, 0.12)*0.06 (0.02, 0.09)*
 Age: 40–59 years−0.01(− 0.07, 0.06)−0.01(− 0.07, 0.06)0.07(− 0.01, 0.16)0.01(−0.05, 0.08)
 Sex while Drunk: Yes− 0.01(− 0.03, 0.01)−0.01(− 0.03, 0.01)−0.06(− 0.08, − 0.04)*−0.03(− 0.06, − 0.01)*
  1. Key:- Statistical significance: (*)P < 0.05; (**)P < 0.01; (***)P < 0.001; Reference category: Age [≤20]; education [≤8 grade]; marital status [many sexual partners]; Sex while Drunk [No]; TB [Yes]; Adverse event [Severe] and Thrombocytopenia [No]