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Table 5 Results of a multivariate multilevel model for QOL domain scores

From: Multivariate multilevel modeling of quality of life dynamics of HIV infected patients

Effects

Physical Health

Psychological Score

Level of Independence

Social Relationship

Intercepts

10.8 (7.43, 14.2)**

9.63 (6.28, 12.9)**

12.8 (8.7, 16.98)**

13.5 (9.9, 17.16)*

Time

0.18 (0.01, 0.37)**

0.21 (0.04, 0.38)**

0.05(− 0.27, 0.18)

0.03(− 0.19, 0.14)

Thrombocytopenia: Yes

0.67(− 0.56, 1.89)

0.52(− 0.69, 1.73)

− 2.01(−3.89, − 0.13)*

− 0.33(−1.93, 1.27)

TB: No

0.38 (0.02, 0.74)**

0.01(− 0.35, 0.38)

0.16(− 0.48, 0.80)

0.05(− 0.47, 0.56)

Anemia: No

1.38 (1.17, 2.12)*

− 0.61(− 1.37, 0.15)

−0.58(− 1.35, 0.18)

0.06(− 0.96, 1.09)

Adverse Event: Normal

3.33 (2.11, 4.55)***

1.43 (1.23, 3.18)*

1.64 (0.42, 2.87)

1.64 (1.02, 2.87)*

Adverse Event: Mild

2.86 (1.66, 4.06)*

1.23 (1.03, 2.43)***

−0.08(− 1.98, 1.82)

1.44 (0.18, 3.06)

Adverse Event: Advanced

3.34 (2.16, 4.53)*

1.32 (0.14, 2.51)

− 0.76(− 2.65, 1.13)

0.86(− 0.76, 2.47)

Education: Grade 9–10

0.60 (0.26, 0.88)

0.25(− 0.60, 1.09)

0.53(− 0.41, 1.48)

0.65(− 0.20, 1.50)

Education:> Grade 11 Grade

0.22 (0.01, 0.99)*

1.26 (1.18, 2.89)**

0.54(− 0.79, 1.86)

0.20(− 0.99, 1.39)

Marital Status: Single/no sexual partner

0.20(−1.43, 1.83)

1.25 (0.38, 2.89)

− 0.67(− 2.45, 1.11)

− 0.51(− 2.10, 1.07)

Marital Status: Married (stable sexual partner)

0.13(−1.69, 1.94)

2.14 (1.01, 3.87)*

−1.36(− 3.34, 0.62)

−1.10(− 2.87, 0.67)

Age: 21–39 years

− 0.34(− 1.16, − 0.49)*

0.26(− 0.59, 1.12)

−1.89(− 2.97, − 0.81)*

−1.25(− 2.19, − 0.30)*

Age: 40–59 years

0.26(− 1.30, 1.81)

0.79(− 0.82, 2.39)

−1.49(− 3.48, 0.49)

− 0.09(− 1.84, 1.66)

Sex while drunk: Yes

−0.08(− 0.99, 0.82)

0.22(− 0.72, 1.16)

0.03(− 1.18, 1.24)

− 0.49(− 1.55, 0.57)

Weight

0.01 (0.001, 0.03)*

0.01 (0.002, 0.03)*

0.01(− 0.01, 0.03)

− 0.01(− 0.02, 0.01)

Viral Load

−0.21(− 0.39, − 0.03)

−0.29(− 0.46, − 0.10)*

−0.09(− 0.37, − 0.01)*

−0.06(− 0.30, − 0.01)*

RBC indices

0.15(− 0.09, 0.38)

0.28 (0.04, 0.51)*

− 0.22(− 0.56, 0.13)

0.04(− 0.25, 0.34)

Hb and haematocrit component

−0.04(− 0.26, 0.18)

−0.11(− 0.33, 0.12)

−0.18(− 0.51, 0.15)

0.05(− 0.24, 0.33)

Granulocytes component

−0.05(− 0.23, 0.13)

0.06(− 0.12, 0.25)

− 0.06(− 0.33, 0.21)

0.14(− 0.09, 0.37)

Mononuclear component

0.28 (0.09, 0.48)*

− 0.13(− 0.30, 0.05)

0.21(− 0.05, 0.47)

0.10(− 0.12, 0.32)

Eosinophil component

− 0.04(− 0.12, 0.03)

− 0.07(− 0.15, 0.00)

−0.12(− 0.24, 0.01)

0.04(− 0.07, 0.15)

Liver enzymes abnormality component

−0.08(− 0.04, − 0.08)*

−0.18(− 0.43, − 0.09)*

0.14(−0.12, 0.40)

−0.15(− 0.37, 0.07)

Electrolyte component

−0.06(− 0.22, 0.10)

−0.18(− 0.34, 0.02)

0.28 (0.02, 0.53)*

−0.10(− 0.32, 0.11)

Time Slope

 Thrombocytopenia: Yes

−0.03(− 0.08, 0.01)

−0.02(− 0.06, 0.02)

−0.16 (− 0.23,-0.08)*

0.02(− 0.04, 0.08)

 Viral Load

−0.06(− 0.1, − 0.001)**

−0.01(− 0.09, − 0.002)*

−0.001(− 0.01, 0.01)

−0.001(− 0.01, 0.01)

 Electrolyte component

0.01 (0.001, 0.02)*

0.04 (0.01, 0.06)*

0.00(− 0.01, 0.01)

0.00 (0.00, 0.01)

 RBC indices

0.00(−0.01, 0.01)

−0.01(− 0.02, 0.00)

0.01 (0.00, 0.03)

0.00(− 0.01, 0.01)

 Hb and haematocrit component

0.06 (0.01, 0.09)*

0.02 (0.01, 0.03)*

0.02 (0.01, 0.03)*

0.01 (0.001, 0.02)*

 Granulocytes component

0.00 (0.00, 0.01)

0.00(− 0.01, 0.00)

0.01 (0.00, 0.02)

0.00(− 0.01, 0.01)

 Mononuclear component

0.001(− 0.01, 0.01)

− 0.01(− 0.02, 0.001)

0.02 (0.01, 0.02)*

0.001(− 0.01, 0.002)

 Liver enzymes abnormality component

− 0.01(− 0.02, −  0.001)*

−0.01(− 0.02, 0.001)

−0.01(− 0.02, 0.002)

−0.01(− 0.02, 0.001)

 Weight

0.01 (0.001, 0.02)*

0.01 (0.001, 0.02)*

0.001(− 0.01, 0.01)

0.001(− 0.01, 0.01)

 Adverse Event: Normal

0.03 (0.01, 0.05)**

− 0.03(− 0.11, 0.04)

0.09 (0.01, 0.17)**

−0.04(− 0.12, 0.04)

 Adverse Event: Mild

0.01 (0.008, 0.06)**

−0.03(− 0.11, 0.04)

0.06 (0.03, 0.12)**

−0.04(− 0.12, 0.04)

 Adverse Event: Advanced

−0.04(− 0.12, 0.03)

−0.04(− 0.11, 0.04)

0.08 (0.00, 0.16)**

−0.02(− 0.10, 0.06)

 Anemia: No

0.03 (0.001, 0.07)**

0.02(− 0.01, 0.06)

−0.06(− 0.11, 0.01)

0.001(− 0.04, 0.04)

 Education: Grade 9–10

0.001(− 0.02, 0.02)

0.001(− 0.02, 0.02)

0.04 (0.01, 0.08)***

−0.02(− 0.04, 0.00)

 Education:> Grade 11

−0.01(− 0.04, 0.03)

0.01(− 0.02, 0.04)

0.03 (0.01, 0.09)*

0.01(− 0.03, 0.04)

 Marital Status: Single

0.01(− 0.02, 0.04)

0.00(− 0.04, 0.03)

−0.02(− 0.06, 0.01)

0.03(− 0.01, 0.07)

 Marital Status: Married (stable sexual partner)

−0.01(− 0.05, 0.03)

−0.02(− 0.06, 0.02)

−0.01(− 0.06, 0.03)

0.05 (0.01, 0.10)**

 Age: 21–39 years

0.02 (0.01, 0.04)*

0.00(−0.03, 0.04)

0.07 (0.03, 0.12)*

0.06 (0.02, 0.09)*

 Age: 40–59 years

−0.01(− 0.07, 0.06)

−0.01(− 0.07, 0.06)

0.07(− 0.01, 0.16)

0.01(−0.05, 0.08)

 Sex while Drunk: Yes

− 0.01(− 0.03, 0.01)

−0.01(− 0.03, 0.01)

−0.06(− 0.08, − 0.04)*

−0.03(− 0.06, − 0.01)*

  1. Key:- Statistical significance: (*)P < 0.05; (**)P < 0.01; (***)P < 0.001; Reference category: Age [≤20]; education [≤8 grade]; marital status [many sexual partners]; Sex while Drunk [No]; TB [Yes]; Adverse event [Severe] and Thrombocytopenia [No]