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Table 2 Health-related quality of life measures

From: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain

  Total sample Gender   Angina Classification   Diagnostic Outcome
   Men Women p Typical Angina Pectoris Atypical Angina Pectoris Non-anginal chest discomfort Other chest discomfort p* ObstructiveCAD No obstructive CAD p
SF-12 Physical Health 43.1 (9.3) 44.2 (9.2) 41.8 (9.3) 0.001 41.2 (8.8)abc 43.3 (9.1)ade 46.2 (9.0)bd 46.4 (11.4)ce < 0.001 41.9 (8.9) 43.7 (9.4) 0.072
SF-12 Mental Health 45.7 (9.8) 47.0 (9.8) 44.1 (9.7) < 0.001 44.5 (9.5)ab 45.1 (9.9)cd 47.6 (10.1)ace 51.4 (8.7)bde < 0.001 45.6 (10.0) 45.7 (9.8) 0.117
EQ-5D-3 L Visual Analogue Scale 66.3 (18.8) 67.7 (18.3) 64.5 (19.3) 0.010 64.0 (18.1)ab 65.6 (19.4)cd 69.6 (18.8)ace 76.6 (16.8)bde < 0.001 64.1 (18.3) 67.2 (19.0) 0.111
EQ-5D-3 L Utility Score 0.69 (0.21) 0.71 (0.20) 0.66 (0.21) < 0.001 0.65 (0.21)ab 0.68 (0.20)cd 0.74 (0.20)ac 0.79 (0.22)bd < 0.001 0.67 (0.20) 0.69 (0.21) 0.230
HADS Depression 5.9 (3.95) 5.5 (3.8) 6.4 (4.1) < 0.001 6.5 (4.0)ab 6.1 (3.7)cd 4.8 (3.8)ac 4.6 (4.5)bd < 0.001 6.0 (4.0) 5.8 (4.0) 0.380
HADS Anxiety 7.5 (4.21) 6.9 (4.0) 8.2 (4.3) < 0.001 8.3 (4.1)a 7.5 (4.1)a 6.5 (4.0)a 4.6 (4.5)a < 0.001 7.3 (4.1) 7.6 (4.2) 0.861
  1. Unadjusted values are presented as mean ± SD. p-values are based upon multiple imputation analyses and adjusted for age and gender where appropriate. Possible site effects were accounted for by mixed model analysis
  2. * Pairwise comparisons: angina classification groups with a common superscript differ significantly (p < 0.05). After applying a Bonferroni correction, some of the comparisons between patients with other or non-anginal chest discomfort and atypical angina pectoris do not reach statistical significance
  3. Measures (possible range in parenthesis): SF-12 Physical and Mental Health (0–100), EQ-5D-3 L Visual Analogue Scale (0–100), EQ-5D-3 L Utility Score (−0.0734–1) and HADS Depression and Anxiety (0–21)