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Table 6 Shows the univariate analysis of psychosocial burden of relatives. Interestingly, there is a significant influence of the patient’s age (p value: 0,05), sodium (p value: 0,04) and hepatic encephalopathy (p value: 0,02) on the psychosocial burden of the relative. In addition, all aspects of impaired quality of life of patients such as fatigue (p value: 0,0004), emotional function (p value: < 0,00001), worries (p value: < 0,00001), abdominal symptoms (p value: 0,0002), patient activity (p value: 0,00005) and systemic symptoms (p value: 0,002) are associated with increased psychosocial stress in relatives

From: Impact of acute-on-chronic liver failure and decompensated liver cirrhosis on psychosocial burden and quality of life of patients and their close relatives

Univariate analysis – psychosocial burden of relatives
ParameterOR95% - CIP Value
Age−0,35-0,690-0,0010,05
Sodium-0,87− 1704−0,0300,04
hepatic encephalopathy10,5920,54419,1250,02
fatigue of patient−6,52− 9869− 31790,0004
Emotional function of patient−7,48−10,333− 4622<  0,0001
worries of patient− 7238− 9618− 4847<  0,0001
Abdominal symptoms of patients−5,14− 7669− 26110,0002
Activity of patient−5,66− 8126− 3188<  0,0001
Systemic symptoms of patient−0,32− 0,510−0,1290,002