GRADE issues | Overall GRADE rating | ||||||
---|---|---|---|---|---|---|---|
Nb. of studies | Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | ||
Before diagnosis | 1 [12] | X1 | X2 | X3 | |||
Before treatment | 4 [14, 18-19, 27] | X4, X5 | |||||
During treatment | 2 [16, 18] | X4 | X6 | X3 | |||
≤ 6 months after treatment | 4 [18-19, 27, 34] | X7 | X5 | ||||
> 6 months after treatment | 7 [13, 20-21, 24-25, 27, 35] | X8 | X9, X5 | None apparent10 |