Health-related quality of life of patients diagnosed with COPD in Extremadura, Spain: results from an observational study

Table 4 Results of stepwise multiple regression models for utility (EQ-5D-5L) and total score (SGRQ-C)

Dependent variable	Explanatory variables^a	B coefficient^b	p-value	95% CI	Coefficient of determination
Total score (SGRQ-C)	Intercept	35.604	< 0.001	(29.278; −41.930)	0.431
	Level of severity	21.267	< 0.001	(12.119; 30.416)
	Number of exacerbations in the past 12 months	8.445	< 0.001	(5.140; 11.749)
	Education level	−18.147	< 0.001	(−27.469; −8.824)
	Gender	19.693	< 0.001	(8.864; 30.523)
Utility (EQ-5D-5L)	Intercept	0.763	< 0.001	(0.684; −0.842)	0.296
	Number of exacerbations in the last 12 months	−0.086	< 0.001	(− 0.127; − 0.044)
	Level of severity	−0.176	0.003	(−0.291; − 0.061)
	Education level	0.188	0.002	(0.071; 0.305)
	Gender	−0.157	0.024	(−0.293; − 0.021)

CI confidence interval, EQ-5D-5L EuroQol - 5 dimensions - 5 levels, SGRQ-C St. George Respiratory Questionnaire – COPD
^aExplanatory variables included in the models: gender (0: male (reference category)/1: female), age in years, education level (0: no education and primary education (reference category)/1: secondary and university education), level of severity (0: GOLD I-II (reference category)/1: GOLD III-IV), number of exacerbations in the last 12 months and number of comorbidities
^bUnstandardized B coefficient

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