Table 1 Baseline demographic and clinical characteristics of SCD patients prescribed HU
Patient characteristics | Sickle cell patients prescribed HU | |
|---|---|---|
(N = 3999) | ||
N/Mean | %/SD | |
Age (years) | 19.24 | 11.85 |
Age Group | ||
 < 2 | 26 | 0.7% |
 2–5 | 327 | 8.2% |
 6–11 | 786 | 19.7% |
 12–17 | 933 | 23.3% |
 18–30 | 1272 | 31.8% |
 31–45 | 501 | 12.5% |
 ≥ 46 | 154 | 3.9% |
Sex | ||
 Male | 2033 | 50.8% |
 Female | 1966 | 49.2% |
Race/Ethnicity | ||
 White | 111 | 2.8% |
 Black | 2933 | 73.3% |
 Hispanic | 296 | 7.4% |
 Other | 33 | 0.8% |
 Unknown | 626 | 15.7% |
Geographic Region | ||
 Northeast | 1335 | 33.4% |
 North Central | 590 | 14.8% |
 South | 1501 | 37.5% |
 West | 573 | 14.3% |
Charlson Comorbidity Index Score | 0.60 | 0.99 |
 0 | 2447 | 61.2% |
 1 | 1035 | 25.9% |
 2–3 | 440 | 11.0% |
 4+ | 77 | 1.9% |
Individual Comorbid Conditions (≥5%) | ||
 Fever | 1255 | 31.4% |
 Asthma | 811 | 20.3% |
 Infectious and parasitic diseases | 798 | 20.0% |
 Acute chest syndrome | 623 | 15.6% |
 Constipation | 485 | 12.1% |
Upper respiratory tract infections | 462 | 11.6% |
Aseptic (avascular) bone necrosis | 307 | 7.7% |
Iron overload | 298 | 7.5% |
Gallstones | 214 | 5.4% |
Chronic pain | 205 | 5.1% |
Neoplasms benign and malignant | 198 | 5.0% |
Sepsis | 198 | 5.0% |