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Table 4 Summary of multiple linear regression analyses predicting proxy-reported generic and disease-specific HRQoL of patients with PM/ICD

From: Health-related quality of life outcomes in pediatric patients with cardiac rhythm devices: a cross-sectional study with case-control comparison

Generic HRQoL Generic overall HRQoL (n = 70) Physical Health Summary Psychosocial Health Summary
Predictor variable B SEB β t p B SEB β t p B SEB β t p
 Female sex −2.98 3.49 −.10 −.86 .40 −4.54 3.91 −.13 − 1.16 .25 −1.43 3.59 −.05 −.40 .69
 Age at assessment (years) .47 .55 .14 .85 .39 .33 .62 .09 .53 .60 .61 .57 .19 1.08 .29
 Time since initial device implant (years) −.66 .53 −.19 −1.25 .22 −.64 .59 −.17 − 1.08 .28 −.67 .54 −.20 −1.24 .22
 Device type (PM or ICD) 2.12 6.35 .06 .33 .74 2.01 7.11 .05 .28 .78 2.23 6.53 .06 .34 .73
 Structural congenital heart disease 2.69 4.10 .09 .66 .51 3.46 4.59 .10 .75 .45 1.93 4.21 .07 .46 .65
 Current cardiac medication −12.73 5.14 −.39 −2.48 .02 −16.45 5.75 −.44 −2.86 .006 −9.02 5.28 −.28 −1.71 .09
 Total length of cardiac hospitalization (days) −.05 .04 −.18 −1.27 .21 −.04 .04 −.13 −.93 .36 −.06 .04 −.22 −1.45 .15
 Other non-cardiac chronic disease −8.69 4.50 −.22 −1.93 .06 −10.20 5.04 −.23 −2.03 .05 −7.19 4.62 −.19 −1.56 .13
  F = 2.78, p = .01, R2 = .27, R2adjusted = .17 F = 3.11, p = .005, R2 = .29, R2adjusted = .20 F = 1.93, p = .07, R2 = .20, R2adjusted = .10
Disease-specific HRQoL Disease-specific overall HRQoL (n = 66)           
Predictor variable B SEB β t p           
 Female sex −4.14 3.54 −.13 −1.17 .25           
 Age at assessment (years) 1.06 .55 .31 1.91 .06           
 Time since initial device implant (years) .06 .53 .02 .10 .92           
 Device type (PM or ICD) 12.03 6.43 .29 1.87 .07           
 Structural congenital heart disease −7.72 4.21 −.24 −1.83 .07           
 Current cardiac medication −4.50 5.10 −.13 −.88 .38           
 Total length of cardiac hospitalization (days) −.04 .04 −.14 −.98 .33           
 Other non-cardiac chronic disease −5.88 4.50 −.14 −1.31 .20           
  F = 4.17, p ≤ .001, R2 = .37, R2adjusted = .28           
  1. Device type coded as 0 = ICD, 1 = PM; Structural congenital heart disease coded as 0 = no, 1 = yes; Current cardiac medication coded as 0 = no, 1 = yes; Other chronic disease coded as 0 = no, 1 = yes (any other chronic disease than heart disease)
  2. B Regression coefficient (unstandardized), SEB Standard error of the regression coefficient, β Standardized regression coefficient
  3. Significant values are indicated in bold