Table 4 Statistical and clinical effects according to planned a priori sample size achievement
Scenario per n° of trials (total = 38a) | N° of powered trials (%) | N° of unpowered trials (%) |
|---|---|---|
A) statistically significant and clinically relevant (n = 14) | 7 (50) | 7 (50) |
B) statistically significant but not clinically relevant (n = 8) | 1 (12) | 7 (87) |
C) not statistically significant but clinically relevant (n = 1) | 0 | 1 (100) |
D) not statistically significant and not clinically relevant (n = 15) | 6 (40) | 9 (60) |
Totals | 14 (37) | 24 (63) |