Table 2 Summary statistics of health state utility (HSU) in head and neck cancer
Initial treatment at early stage | Initial treatment at locally advanced stage | Initial treatment with distant metastasis | Relapse treatment in the follow-up | Relapse-free in the follow-up | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n (%) | Mean (std) | n (%) | Mean (std) | n (%) | Mean (std) | n (%) | Mean (std) | n (%) | Mean (std) | ||
Overall | 87,965 (100) | 0.525 (0.183) | 181,094 (100) | 0.558 (0.174) | 33,573 (100) | 0.451 (0.224) | 91,929 (100) | 0.530 (0.186) | 256,816 (100) | 0.546 (0.170) | |
Age at diagnosis | 18–49 | 10,519 (12.0) | 0.699 (0.101) | 25,615 (14.1) | 0.647 (0.114) | 3,917 (11.7) | 0.555 (0.187) | 14,316 (15.6) | 0.590 (0.160) | 36,532 (14.2) | 0.635 (0.117) |
50–54 | 9,271 (10.5) | 0.700 (0.101) | 29,629 (16.4) | 0.632 (0.122) | 5,298 (15.8) | 0.524 (0.193) | 16,529 (18.0) | 0.582 (0.162) | 36,010 (14.0) | 0.646 (0.131) | |
55–59 | 11,770 (13.4) | 0.624 (0.108) | 36,029 (19.9) | 0.617 (0.130) | 6,808 (20.3) | 0.439 (0.198) | 19,071 (20.7) | 0.569 (0.164) | 43,821 (17.1) | 0.638 (0.128) | |
60–64 | 13,182 (15.0) | 0.554 (0.113) | 32,872 (18.2) | 0.562 (0.145) | 6,578 (19.6) | 0.486 (0.213) | 16,389 (17.8) | 0.498 (0.181) | 43,704 (17.0) | 0.540 (0.121) | |
65–69 | 9,443 (10.7) | 0.533 (0.122) | 20,237 (11.2) | 0.519 (0.148) | 4,290 (12.8) | 0.427 (0.220) | 9,753 (10.6) | 0.510 (0.178) | 28,573 (11.1) | 0.531 (0.131) | |
70–74 | 9,262 (10.5) | 0.415 (0.140) | 14,551 (8.0) | 0.450 (0.167) | 2,627 (7.8) | 0.392 (0.217) | 7,077 (7.7) | 0.467 (0.197) | 23,060 (9.0) | 0.446 (0.137) | |
75–79 | 9,864 (11.2) | 0.422 (0.140) | 11,333 (6.3) | 0.416 (0.182) | 1,994 (5.9) | 0.286 (0.241) | 4,852 (5.3) | 0.432 (0.198) | 21,273 (8.3) | 0.428 (0.163) | |
80+ | 14,654 (16.7) | 0.316 (0.151) | 10,828 (6.0) | 0.306 (0.231) | 2,061 (6.1) | 0.269 (0.248) | 3,942 (4.3) | 0.317 (0.198) | 23,843 (9.3) | 0.324 (0.171) | |
Comorbidities | 0 | 46,845 (53.3) | 0.571 (0.145) | 80,616 (44.5) | 0.602 (0.128) | 9,555 (28.5) | 0.501 (0.176) | 28,200 (30.7) | 0.568 (0.145) | 127,033 (49.5) | 0.583 (0.125) |
1 | 21,650 (24.6) | 0.519 (0.171) | 53,581 (29.6) | 0.567 (0.158) | 11,009 (32.8) | 0.478 (0.202) | 29,366 (31.9) | 0.545 (0.171) | 68,498 (26.7) | 0.547 (0.157) | |
2 | 10,886 (12.4) | 0.459 (0.206) | 26,311 (14.5) | 0.515 (0.193) | 6,914 (20.6) | 0.428 (0.234) | 17,726 (19.3) | 0.512 (0.197) | 33,774 (13.2) | 0.505 (0.198) | |
≥3 | 8,584 (9.8) | 0.369 (0.243) | 20,586 (11.4) | 0.417 (0.244) | 6,095 (18.2) | 0.349 (0.275) | 16,637 (18.1) | 0.456 (0.232) | 27,511 (10.7) | 0.429 (0.255) | |