Table 3 Multiple linear regression models on long-term fatigue using MFI assessment
Hodgkin lymphoma | Non-Hodgkin lymphomas | |||||
|---|---|---|---|---|---|---|
Coef β (sd) | P-value | Coef β (sd) | P-value | |||
General fatigue | Reference score (intercept) | 23.7 (1.9) | < 0.001 | 32.0 (2.9) | < 0.001 | |
Age at time of fatigue assessment | ||||||
per 10-yr increase | 20–69 yrs | 1.3 (0.6) | 0.047 | −1.2 (0.7) | 0.089 | |
≥ 70 yrs | 5.0 (5.1) | 0.328 | 9.5 (1.7) | < 0.001 | ||
Years since treatment start | ||||||
per 10-yr increase | 1.9 (0.8) | 0.018 | −1.3 (1.0) | 0.194 | ||
Gender | Male | 0.0 | 0.0 | |||
Female | 7.1 (1.2) | < 0.001 | 5.2 (1.3) | < 0.001 | ||
Education level a | High | 0.0 | 0.0 | |||
Low | 3.5 (1.4) | 0.015 | 1.6 (1.4) | 0.240 | ||
Cohabitation status | ||||||
living with partner | Yes | 0.0 | 0.0 | |||
No | 4.7 (1.6) | 0.003 | 1.4 (1.4) | 0.322 | ||
Obesity b | No | 0.0 | 0.0 | |||
Yes | 7.6 (2.0) | < 0.001 | 5.8 (1.7) | 0.001 | ||
Health disorders | No | 0.0 | 0.0 | |||
Yes | 14.6 (1.3) | < 0.001 | 15.6 (1.3) | < 0.001 | ||
Physical Fatigue | Reference score (intercept) | 13.3 (1.9) | < 0.001 | 27.4 (3.0) | < 0.001 | |
Age at time of fatigue assessment | ||||||
per 10-yr increase | 20–69 yrs | 2.3 (0.6) | 0.001 | −1.6 (0.7) | 0.033 | |
≥ 70 yrs | 10.1 (5.0) | 0.045 | 12.2 (1.7) | < 0.001 | ||
Years since treatment start | ||||||
per 10-yr increase | 3.7 (0.8) | < 0.001 | −1.0 (1.0) | 0.328 | ||
Gender | Male | 0.0 | 0.0 | |||
Female | 5.2 (1.2) | < 0.001 | 2.8 (1.3) | 0.034 | ||
Education level a | High | 0.0 | 0.0 | |||
Low | 3.5 (1.4) | 0.012 | 2.6 (1.4) | 0.074 | ||
Cohabitation status | ||||||
living with partner | Yes | 0.0 | 0.0 | |||
No | 4.8 (1.6) | 0.002 | 2.2 (1.5) | 0.150 | ||
Obesity b | No | 0.0 | 0.0 | |||
Yes | 10.3 (1.9) | < 0.001 | 6.9 (1.8) | < 0.001 | ||
Health disorders | No | 0.0 | 0.0 | |||
Yes | 14.7 (1.3) | < 0.001 | 15.6 (3.0) | < 0.001 | ||
Reduced activity | Reference score (intercept) | 11.4 (1.7) | < 0.001 | 17.3 (2.6) | < 0.001 | |
Age at time of fatigue assessment | ||||||
per 10-yr increase | 20–69 yrs | 3.4 (0.6) | < 0.001 | 1.6 (0.6) | 0.011 | |
≥ 70 yrs | 12.8 (4.6) | 0.005 | 11.3 (1.5) | < 0.001 | ||
Years since treatment start | ||||||
per 10-yr increase | 1.6 (0.7) | 0.025 | −1.0 (0.9) | 0.273 | ||
Gender | Male | 0.0 | 0.0 | |||
Female | −0.4 (1.1) | 0.723 | −0.6 (1.2) | 0.611 | ||
Education level a | High | 0.0 | 0.0 | |||
Low | 4.2 (1.3) | 0.001 | 2.2 (1.3) | 0.074 | ||
Cohabitation status | ||||||
living with partner | Yes | 0.0 | 0.0 | |||
No | 7.9 (1.4) | < 0.001 | 3.2 (1.3) | 0.015 | ||
Obesity b | No | 0.0 | 0.0 | |||
Yes | 5.6 (1.7) | 0.001 | 5.2 (1.5) | 0.001 | ||
Health disorders | No | 0.0 | 0.0 | |||
Yes | 9.2 (1.2) | < 0.001 | 8.9 (1.2) | < 0.001 | ||
Reduced motivation | Reference score (intercept) | 7.4 (1.6) | < 0.001 | 12.6 (2.6) | < 0.001 | |
Age at time of fatigue assessment | ||||||
per 10-yr increase | 20–69 yrs | 3.7 (0.5) | < 0.001 | 0.8 (0.6) | 0.212 | |
≥ 70 yrs | 12.7 (4.2) | 0.003 | 10.3 (1.5) | < 0.001 | ||
Years since treatment start | ||||||
per 10-yr increase | 1.5 (0.7) | 0.022 | −0.5 (0.9) | 0.582 | ||
Gender | Male | 0.0 | 0.0 | |||
Female | 0.4 (1.0) | 0.692 | 2.6 (1.1) | 0.020 | ||
Education level a | High | 0.0 | 0.0 | |||
Low | 4.0 (1.2) | 0.001 | 3.4 (1.2) | 0.005 | ||
Cohabitation status | ||||||
living with partner | Yes | 0.0 | 0.0 | |||
No | 6.0 (1.3) | < 0.001 | 4.7 (1.3) | < 0.001 | ||
Obesity b | No | 0.0 | 0.0 | |||
Yes | 7.1 (1.6) | < 0.001 | 4.0 (1.5) | 0.008 | ||
Health disorders | No | 0.0 | 0.0 | |||
Yes | 6.5 (1.1) | < 0.001 | 8.4 (1.2) | < 0.001 | ||
Mental fatigue | Reference score (intercept) | 19.3 (1.8) | < 0.001 | 21.4 (2.9) | 0.002 | |
Age at time of fatigue assessment | ||||||
per 10-yr increase | 20–69 yrs | 0.6 (0.6) | 0.318 | −0.9 (0.7) | 0.211 | |
≥ 70 yrs | −0.2 (4.9) | 0.965 | 3.4 (1.7) | 0.043 | ||
Years since treatment start | ||||||
per 10-yr increase | −0.6 (0.8) | 0.431 | −0.2 (1.0) | 0.866 | ||
Gender | Male | 0.0 | 0.0 | |||
Female | 3.4 (1.2) | 0.005 | 1.4 (1.3) | 0.282 | ||
Education level a | High | 0.0 | 0.0 | |||
Low | 4.7 (1.4) | 0.001 | 4.2 (1.4) | 0.002 | ||
Cohabitation status | ||||||
living with partner | Yes | 0.0 | 0.0 | |||
No | 4.4 (1.5) | 0.003 | 4.0 (1.4) | 0.006 | ||
Obesity b | No | 0.0 | 0.0 | |||
Yes | 2.6 (1.9) | 0.159 | −0.1 (1.7) | 0.929 | ||
Health disorders | No | 0.0 | 0.0 | |||
Yes | 10.7 (1.3) | < 0.001 | 10.2 (1.3) | < 0.001 | ||