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Table 3 Correlation between SF-8 health profile dimensions and PVR, BNP, and Peak VO2 at baseline

From: Medium-term health-related quality of life in patients with pulmonary arterial hypertension treated with goal-oriented sequential combination therapy based on exercise capacity

 

PVR

Plasma BNP

Peak VO2

r

P

r

P

r

P

PF

−0.500

<0.001

−0.496

<0.001

0.501

<0.001

RP

−0.529

<0.001

−0.513

<0.001

0.657

<0.001

BP

0.050

0.754

−0.125

0.436

0.179

0.263

GH

−0.455

0.003

−0.327

0.037

0.396

0.010

VT

−0.390

0.012

−0.529

<0.001

0.531

<0.001

SF

−0.272

0.086

−0.349

0.025

0.427

0.005

RE

−0.337

0.031

−0.428

0.005

0.494

0.001

MH

−0.134

0.402

−0.213

0.181

0.211

0.186

PCS

−0.427

0.005

−0.417

0.007

0.411

0.003

MCS

−0.158

0.323

−0.280

0.076

0.299

0.037

  1. PVR Pulmonary vascular resistance, BNP Brain natriuretic peptide
  2. Health-related quality of life was assessed by using the Medical Outcomes Study Short Form Health Survey (SF-8), which consists of eight items, each representing one health profile dimension: PF Physical functioning; RP Role functioning – physical, BP Bodily pain, GH General health perception, VT Vitality, SF Social functioning, RE Role functioning – emotional; and MH Mental health. Physical component summary (PCS) and mental component summary (MCS) scores were compared with demographically adjusted United States norms and with historical controls