EQ-5D | Baseline | 3 months | 6 months | 9 months | ||||
---|---|---|---|---|---|---|---|---|
Non-bDMARDs | bDMARDs | Non-bDMARDs | bDMARDs | Non-bDMARDs | bDMARDs | Non-bDMARDs | bDMARDs | |
Mobility, n (%) | N = 86 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
 Level 1 | 43 (50.0) | 50 (40.7) | 40 (58.8) | 45 (39.1) | 49 (67.1) | 48 (39.7) | 47 (60.3) | 54 (45.4) |
 Level 2 | 43 (50.0) | 72 (58.5) | 28 (41.2) | 70 (60.9) | 24 (32.9) | 73 (60.3) | 31 (39.7) | 63 (52.9) |
 Level 3 | 0 (0.0) | 1 (0.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (1.7) |
Self-care, n (%) | N = 86 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
 Level 1 | 60 (69.8) | 77 (62.6) | 45 (66.2) | 68 (59.1) | 45 (61.6) | 63 (52.1) | 46 (59.0) | 61 (51.3) |
 Level 2 | 26 (30.2) | 46 (37.4) | 23 (33.8) | 47 (40.9) | 28 (38.4) | 58 (47.9) | 32 (41.0) | 56 (47.1) |
 Level 3 | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (1.7) |
Usual activities, n (%) | N = 85 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
 Level 1 | 33 (38.8) | 39 (31.7) | 34 (50.0) | 41 (35.7) | 34 (46.6) | 37 (30.6) | 35 (44.9) | 32 (26.9) |
 Level 2 | 50 (58.8) | 84 (68.3) | 34 (50.0) | 73 (63.5) | 39 (53.4) | 82 (67.8) | 43 (55.1) | 85 (71.4) |
 Level 3 | 2 (2.4) | 0 (0.0) | 0 (0.0) | 1 (0.9) | 0 (0.0) | 2 (1.7) | 0 (0.0) | 2 (1.7) |
Pain/discomfort, n (%) | N = 86 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
 Level 1 | 28 (32.6) | 33 (26.8) | 28 (41.2) | 25 (21.7) | 33 (45.2) | 25 (20.7) | 38 (48.7) | 25 (21.0) |
 Level 2 | 56 (65.1) | 80 (65.0) | 38 (55.9) | 84 (73.0) | 39 (53.4) | 88 (72.7) | 36 (46.2) | 82 (68.9) |
 Level 3 | 2 (2.3) | 10 (8.1) | 2 (2.9) | 6 (5.2) | 1 (1.4) | 8 (6.6) | 4 (5.1) | 12 (10.1) |
Anxiety/depression, n (%) | N = 86 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
 Level 1 | 31 (36.0) | 43 (35.0) | 30 (44.1) | 42 (36.5) | 38 (52.1) | 34 (28.1) | 37 (47.4) | 28 (23.5) |
 Level 2 | 36 (41.9) | 50 (40.7) | 30 (44.1) | 47 (40.9) | 30 (41.1) | 60 (49.6) | 31 (39.7) | 60 (50.4) |
 Level 3 | 19 (22.1) | 30 (24.4) | 8 (11.8) | 26 (22.6) | 5 (6.8) | 27 (22.3) | 10 (12.8) | 31 (26.1) |
EQ VAS score, Mean ± SD | N = 86 | N = 123 | N = 68 | N = 115 | N = 73 | N = 120 | N = 78 | N = 119 |
67.0 ± 20.2 | 66.0 ± 20.2 | 71.4 ± 20.9 | 67.2 ± 19.3 | 75.9 ± 18.8 | 66.7 ± 18.7 | 75.9 ± 19.0 | 67.7 ± 18.8 | |
Total EQ-5D score, Mean ± SD | N = 85 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
0.60 ± 0.32 | 0.54 ± 0.32 | 0.69 ± 0.31 | 0.56 ± 0.30 | 0.73 ± 0.26 | 0.54 ± 0.30 | 0.68 ± 0.32 | 0.50 ± 0.34 | |
Adjusted total EQ-5D scorea, Least-squares mean ± SE | N = 85 | N = 123 | N = 68 | N = 115 | N = 73 | N = 121 | N = 78 | N = 119 |
0.59 ± 0.04 | 0.55 ± 0.03 | 0.66 ± 0.03 | 0.55 ± 0.03 | 0.70 ± 0.03 | 0.53 ± 0.03 | 0.65 ± 0.04 | 0.49 ± 0.03 |