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Table 1 Internal consistency reliability and clinical and concurrent validity of the FACT-M and MCC-specific scores in the mMCC population

From: Correction to: Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma

FACT-M Subscales and Summary scores

# items

Cronbach’s alpha[a]

Scale structure

ECOG PS (mean [SD])

EQ-5D VAS

EQ-5D index

Range of item-subscale correlations[b]

Convergent[c]/Divergent[d] validity (% of items)

0 (n = 39)

1 (N = 31)

p-value[e]

Correlation[b]

Correlation [b]

FACT-G subscales

 Physical well-being (PWB)

7

0.86

0.49–0.81

100/ 57

23.21 (5.02)

20.10 (6.08)

0.0221

0.59

0.75

 Social/Family well-being (SWB)

7

0.81

0.41–0.86

100/ 71

23.03 (4.78)

21.49 (5.30)

0.2065

0.19

0.24

 Emotional well-being (EWB)

6

0.83

0.53–0.75

100/ 67

17.97 (4.22)

16.87 (4.95)

0.3179

0.36

0.53

 Functional well-being (FWB)

7

0.87

0.49–0.82

100/ 71

17.41 (6.68)

15.48 (5.90)

0.2113

0.44

0.63

Melanoma-specific subscales

 Melanoma Subscale (MS)

16

0.85

0.24–0.85

75 / 31

51.64 (8.93)

49.10 (9.02)

0.2427

0.55

0.75

 Melanoma surgery Scale (MSS)

8

0.84

0.15–0.81

88 / 63

26.51 (6.19)

25.58 (6.03)

0.5290

0.26

0.51

Summary scales

 FACT-M TOI

30

0.94

–

–

92.26 (18.75)

84.68 (19.40)

0.1026

0.58

0.78

 FACT-G total score

27

0.94

–

–

81.62 (17.25)

73.95 (17.62)

0.0713

0.50

0.67

 FACT-M total score

43

0.96

–

–

133.26 (24.66)

123.04 (25.21)

0.0926

0.55

0.74

MCC-Specific scores

 Physical function score (PF)

6

0.88

–

–

16.38 (5.67)

13.71 (5.54)

0.0519

0.52

0.72

 Psychological impact score (PI)

6

0.85

–

–

17.82 (4.40)

16.87 (5.18)

0.4101

0.36

0.52

 MCC summary score

12

0.91

–

–

34.21 (8.99)

30.58 (9.94)

0.1145

0.49

0.69

  1. # number, ECOG PS Eastern Cooperative Oncology Group performance score, MCC Merkel cell carcinoma, PAS PRO analysis set, SD Standard deviation, TOI Trial Outcome Index
  2. [a] Recommended threshold α > 0.7; [b] Pearson correlation coefficients; [c] % of items correlated with its own dimension ≥0.4; [d] % of items correlated with its own dimension higher that the correlation with any other dimension; [e] p-value from t-test of score between the two ECOG performance status groups at baseline
  3. Internal consistency reliability and clinical validity were assessed in the PAS (N = 70)
  4. ECOG PS: 0 = Fully active; 1 = Restricted in physically strenuous activity