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Table 7 HRQOL changes from baseline (T0) and 1-year follow-up (T1) between treated and untreated patients

From: Psychometric properties of the quality of life in short statured youth (QoLISSY) questionnaire within the course of growth hormone treatment

 

Treated (IGHD/SGA)

Untreated (ISS)

 

Patient-reports

M (SD) (N = 33)

M (SD (N = 18)

F

p

Ŋp2

Physical

T0

48.99 (26.96)

69.91 (18.22)

8.51

< .01

.15

T1

62.65 (22.85)

61.94 (27.57)

Social

T0

45.67 (26.64)

66.42 (20.42)

14.76

< .01

.24

T1

62.04 (25.86)

58.51 (23.70)

Emotional

T0

47.06 (24.86)

70.71 (26.56)

11.68

< .01

.20

T1

61.24 (23.29)

62.18 (26.80)

Coping

T0

60.98 (22.29)

67.78 (21.62)

2.44

.13

.05

T1

60.56 (16.19)

57.08 (18.03)

Beliefs

T0

41.86 (30.03)

68.06 (31.21)

3.23

.08

.06

T1

46.59 (33.88)

56.60 (28.72)

Total score a

T0

48.88 (24.17)

69.01 (19.50)

9.72

< .01

.16

T1

61.60 (22.88)

60.88 (24.20)

KIDSCREEN-10 Index

T0

54.80 (12.06)

51.93 (9.10)

1.06

.30

.02

T1

55.80 (10.58)

55.66 (13.89)

Parents-reports

M (SD) (N = 78)

M (SD) (N = 20)

F

p

Ŋp2

Physical

T0

46.78 (25.54)

62.50 (25.90)

.14

.71

.00

T1

54.11 (25.04)

63.92 (26.11)

Social

T0

48.20 (24.64)

58.62 (24.46)

.79

.38

.01

T1

55.49 (25.73)

58.50 (27.39)

Emotional

T0

47.88 (24.37)

58.19 (23.58)

.85

.36

.01

T1

55.89 (24.63)

60.16 (27.56)

Coping

T0

48.30 (17.03)

59.89 (21.49)

1.56

.22

.02

T1

50.42 (15.68)

55.18 (24.01)

Beliefs

T0

51.92 (28.97)

61.25 (32.23)

.24

.62

.00

T1

50.88 (29.08)

57.19 (36.01)

Future

T0

52.05 (30.38)

70.25 (25.31)

3.33

.07

.03

T1

59.73 (28.37)

63.56 (29.28)

Effects on parents

T0

49.48 (22.10)

59.84 (24.41)

.25

.62

.00

T1

55.62 (21.70)

58.99 (27.36)

Total score a

T0

50.56 (23.57)

60.97 (22.46)

1.33

.25

.01

T1

57.34 (23.31)

60.63 (25.05)

KIDSCREEN-10 Index

T0

50.90 (10.16)

51.75 (7.84)

2.71

.10

.03

T1

51.75 (7.84)

48.56 (12.11)

  1. Note: Analysis: Univariate analyses of covariance. M = Mean, SD = Standard deviation, F=F-value, p = P-value, Ŋp2 = partial eta square, IGHD = idiopathic growth hormone deficiency, SGA = short for gestational age, ISS = idiopathic short stature, T0 = baseline, T1 = 12 month after start of hGH treatment
  2. a sum of the scales physical, social, emotional