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Table 4 GRADE Summary of findings. Outcome: Urinary symptoms

From: Quality of life in bladder cancer patients receiving medical oncological treatment; a systematic review of the literature

 

GRADE issues

Overall GRADE rating

 

Nb. of studies

Risk of bias

Inconsistency

Indirectness

Imprecision

Publication bias

 

Before diagnosis

2 [18, 27]

 

X1

X2

X3

 

Before treatment

0

–

–

–

–

–

N/A

During treatment

2 [16, 18]

 

X4

X5

X3

 

≤ 6 months after treatment

2 [18, 27]

 

X1

 

X3

 

> 6 months after treatment

8 [20, 21, 23,24,25,26,27, 35]

X6, X7

X8

X9

 

None apparent10

  1. 11 out of 2 scores from non-validated questionnaire [27]
  2. 2No studies before CT for metastatic disease or as neoadjuvant treatment
  3. 3Large difference in populations hence diverging scores
  4. 4Small number of patients
  5. 5Only one study representing metastatic population, no studies representing neoadjuvant population
  6. 6Diverging scores from one study [27]
  7. 7Small number of patients for [27] at time point 36 months
  8. 8Different incl. Non-validated questionnaires used
  9. 9All patients after CT/RT or RT alone
  10. 10As estimated by forest plot
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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