Table 1 General information for all studies selected (N = 46)
| Â | Number | Percent |
|---|---|---|
Disease stage | ||
 Metastatic / Advanced | 20 | 43.5 |
 Non metastatic / Local | 5 | 10.9 |
 Both | 12 | 26.1 |
 Unclear or not reported | 9 | 19.5 |
Type of study | ||
 Randomized clinical trials | 10 | 21.7 |
 Prospective cohort study | 23 | 50 |
 Other | 13 | 28.3 |
International study | ||
 Yes | 9 | 19.6 |
 No | 37 | 80.4 |
Multicenter study | ||
 Yes | 22 | 47.8 |
 No | 13 | 28.3 |
 Unclear or not reported | 11 | 23.9 |
Questionnaires | ||
 EORTC QLQ-C30 | 10 | 21.7 |
 EORTC QLQ-C15-PAL | 2 | 4.3 |
 EORTC specific modules | 6 | 13.0 |
 FACT-G | 1 | 2.2 |
 Other FACT questionnaires | 13 | 21.7 |
 Other multidimensional questionnaires | 8 | 17.4 |
 Other specific PRO questionnaires | 13 | 28.2 |