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Table 5 Factors that moderate the correlations of anxiety and depression between adults with cancer and their family caregivers

From: The impact of depression and anxiety on quality of life in Chinese cancer patient-family caregiver dyads, a cross-sectional study

Factors 5a: AC-related variables 5b: FC-related variables
nc Correlation of Anx Correlation of Dep nc Correlation of Anx Correlation of Dep
r P-value r P-value r P-value r P-value
Age (years)
  < 30 21 0.391 0.089 0.525a 0.017 83 0.414 b <0.001 0.354b 0.001
 30 ~  45 127 0.156 0.082 0.122 0.174 217 0.320 b <0.001 0.282b < 0.001
 46 ~  60 247 0.424b < 0.001 0.358b < 0.001 203 0.327 b < 0.001 0.309b < 0.001
  > 60 218 0.312b < 0.001 0.335b < 0.001 103 0.308b 0.002 0.363b < 0.001
Gender
 Male 309 0.373b < 0.001 0.330b < 0.001 302 0.274b < 0.001 0.284b < 0.001
 Female 310 0.269b < 0.001 0.289b < 0.001 320 0.352b < 0.001 0.319b < 0.001
Marital status
 Married 570 0.323b < 0.001 0.312b < 0.001 555 0.303b < 0.001 0.290b < 0.001
 Not married 53 0.225 0.117 0.238 0.086 67 0.486b < 0.001 0.513b < 0.001
FCs’ relationship with patients
 Spouses       334 0.330b < 0.001 0.360b < 0.001
 Offspring       209 0.387b < 0.001 0.335b < 0.001
 Parents       20 0.425 0.070 0.454a 0.044
 Sibling       39 0.028 0.862 −0.128 0.438
 Others       21 0.013 0.954 −0.025 0.916
Education levels
 Primary school or less 346 0.269b < 0.001 0.231b < 0.001 246 0.263b <0.001 0.202b 0.001
 High school 194 0.376b <0.001 0.427b <0.001 217 0.339b <0.001 0.348b <0.001
 University or above 81 0.308b 0.006 0.280a 0.011 156 0.335b <0.001 0.355b <0.001
Working status
 Working 360 0.297b <0.001 0.307b <0.001 400 0.268b <0.001 0.264b <0.001
 Not working 259 0.322b <0.001 0.280b <0.001 220 0.385b <0.001 0.353b <0.001
Duration in their role as a family caregiver
  < 6 months       340 0.228b <0.001 0.189b <0.001
 6 months~ 2 years       186 0.505b <0.001 0.528b <0.001
  > 2 ~ 5 years       52 0.257 0.066 0.300a 0.029
  > 5 years       37 0.105 0.538 0.255 0.128
Informed about the disease
 Ill-informed 256 0.276b <0.001 0.233b <0.001 151 0.303b <0.001 0.162a 0.046
 Partly informed 248 0.361b <0.001 0.360b <0.001 273 0.319b <0.001 0.332b <0.001
 Well-informed 115 0.149 0.112 0.173 0.065 198 0.310b <0.001 0.351b <0.001
Time spent by family caregivers in caring for patients / day
  < 2 h       54 0.361b 0.007 0.234 0.085
 2~4 h       85 0.344a 0.001 0.391b <0.001
  > 4~6 h       72 0.400b <0.001 0.361b 0.002
  > 6~8 h       84 0.405b <0.001 0.425b <0.001
  > 8 h       322 0.242b <0.001 0.217b <0.001
Type of cancer
 Breast cancer 67 0.376b 0.002 0.351b 0.003      
 Ovarian and cervical cancer 88 0.176 0.101 0.157 0.135      
 Esophageal and gastric cancer 147 0.551b <0.001 0.485b <0.001      
 Colorectal cancer 83 0.306b 0.005 0.228a 0.038      
 Liver cancer 59 0.110 0.410 0.168 0.203      
 Lung cancer 85 0.203 0.062 0.295b 0.007      
 Others 74 0.342b <0.001 0.306b 0.008      
Type of treatment
 Chemotherapy 267 0.330b <0.001 0.305b <0.001      
 Chemotherapy +surgery 112 0.250b 0.009 0.202a 0.035      
 Chemotherapy +radiotherapy 160 0.380b <0.001 0.361b <0.001      
 Chemotherapy+ others 80 0.207 0.067 0.270a 0.015      
5c: Family-related variables
Relationship with their family members pre-cancer
 Very good 459 0.321b <0.001 0.326b <0.001      
 Normal 157 0.252b 0.001 0.172a 0.032      
 Poor 8 0.219 0.602 −0.156 0.712      
Relationship with family members changed post-cancer
 Improving 213 0.345b <0.001 0.390b <0.001      
 No change 377 0.293b <0.001 0.250b <0.001      
 Worsening 31 0.312 0.088 0.246 0.183      
Financial burden on the family due to cancer treatment
 Serious 400 0.316b <0.001 0.346b <0.001      
 Moderate 187 0.232b 0.002 0.154a 0.035      
 Mild or None 33 0.613b <0.001 0.380a 0.029      
  1. Note: AC Adults with Cancer, FC Family Caregivers, Anx Anxiety, Dep Depression, Correlation of Anx Correlation of Anx between adults with cancer and their family caregivers, Correlation of Dep Correlation of Dep between adults with cancer and their family caregivers
  2. aCorrelation is significant at the 0.05 level (2-tailed)
  3. bCorrelation is significant at the 0.01 level (2-tailed)
  4. cThe total n does not equal 641 because of missing values