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Table 5 Factors that moderate the correlations of anxiety and depression between adults with cancer and their family caregivers

From: The impact of depression and anxiety on quality of life in Chinese cancer patient-family caregiver dyads, a cross-sectional study

Factors

5a: AC-related variables

5b: FC-related variables

nc

Correlation of Anx

Correlation of Dep

nc

Correlation of Anx

Correlation of Dep

r

P-value

r

P-value

r

P-value

r

P-value

Age (years)

  < 30

21

0.391

0.089

0.525a

0.017

83

0.414 b

<0.001

0.354b

0.001

 30 ~  45

127

0.156

0.082

0.122

0.174

217

0.320 b

<0.001

0.282b

< 0.001

 46 ~  60

247

0.424b

< 0.001

0.358b

< 0.001

203

0.327 b

< 0.001

0.309b

< 0.001

  > 60

218

0.312b

< 0.001

0.335b

< 0.001

103

0.308b

0.002

0.363b

< 0.001

Gender

 Male

309

0.373b

< 0.001

0.330b

< 0.001

302

0.274b

< 0.001

0.284b

< 0.001

 Female

310

0.269b

< 0.001

0.289b

< 0.001

320

0.352b

< 0.001

0.319b

< 0.001

Marital status

 Married

570

0.323b

< 0.001

0.312b

< 0.001

555

0.303b

< 0.001

0.290b

< 0.001

 Not married

53

0.225

0.117

0.238

0.086

67

0.486b

< 0.001

0.513b

< 0.001

FCs’ relationship with patients

 Spouses

     

334

0.330b

< 0.001

0.360b

< 0.001

 Offspring

     

209

0.387b

< 0.001

0.335b

< 0.001

 Parents

     

20

0.425

0.070

0.454a

0.044

 Sibling

     

39

0.028

0.862

−0.128

0.438

 Others

     

21

0.013

0.954

−0.025

0.916

Education levels

 Primary school or less

346

0.269b

< 0.001

0.231b

< 0.001

246

0.263b

<0.001

0.202b

0.001

 High school

194

0.376b

<0.001

0.427b

<0.001

217

0.339b

<0.001

0.348b

<0.001

 University or above

81

0.308b

0.006

0.280a

0.011

156

0.335b

<0.001

0.355b

<0.001

Working status

 Working

360

0.297b

<0.001

0.307b

<0.001

400

0.268b

<0.001

0.264b

<0.001

 Not working

259

0.322b

<0.001

0.280b

<0.001

220

0.385b

<0.001

0.353b

<0.001

Duration in their role as a family caregiver

  < 6 months

     

340

0.228b

<0.001

0.189b

<0.001

 6 months~ 2 years

     

186

0.505b

<0.001

0.528b

<0.001

  > 2 ~ 5 years

     

52

0.257

0.066

0.300a

0.029

  > 5 years

     

37

0.105

0.538

0.255

0.128

Informed about the disease

 Ill-informed

256

0.276b

<0.001

0.233b

<0.001

151

0.303b

<0.001

0.162a

0.046

 Partly informed

248

0.361b

<0.001

0.360b

<0.001

273

0.319b

<0.001

0.332b

<0.001

 Well-informed

115

0.149

0.112

0.173

0.065

198

0.310b

<0.001

0.351b

<0.001

Time spent by family caregivers in caring for patients / day

  < 2 h

     

54

0.361b

0.007

0.234

0.085

 2~4 h

     

85

0.344a

0.001

0.391b

<0.001

  > 4~6 h

     

72

0.400b

<0.001

0.361b

0.002

  > 6~8 h

     

84

0.405b

<0.001

0.425b

<0.001

  > 8 h

     

322

0.242b

<0.001

0.217b

<0.001

Type of cancer

 Breast cancer

67

0.376b

0.002

0.351b

0.003

     

 Ovarian and cervical cancer

88

0.176

0.101

0.157

0.135

     

 Esophageal and gastric cancer

147

0.551b

<0.001

0.485b

<0.001

     

 Colorectal cancer

83

0.306b

0.005

0.228a

0.038

     

 Liver cancer

59

0.110

0.410

0.168

0.203

     

 Lung cancer

85

0.203

0.062

0.295b

0.007

     

 Others

74

0.342b

<0.001

0.306b

0.008

     

Type of treatment

 Chemotherapy

267

0.330b

<0.001

0.305b

<0.001

     

 Chemotherapy +surgery

112

0.250b

0.009

0.202a

0.035

     

 Chemotherapy +radiotherapy

160

0.380b

<0.001

0.361b

<0.001

     

 Chemotherapy+ others

80

0.207

0.067

0.270a

0.015

     

5c: Family-related variables

Relationship with their family members pre-cancer

 Very good

459

0.321b

<0.001

0.326b

<0.001

     

 Normal

157

0.252b

0.001

0.172a

0.032

     

 Poor

8

0.219

0.602

−0.156

0.712

     

Relationship with family members changed post-cancer

 Improving

213

0.345b

<0.001

0.390b

<0.001

     

 No change

377

0.293b

<0.001

0.250b

<0.001

     

 Worsening

31

0.312

0.088

0.246

0.183

     

Financial burden on the family due to cancer treatment

 Serious

400

0.316b

<0.001

0.346b

<0.001

     

 Moderate

187

0.232b

0.002

0.154a

0.035

     

 Mild or None

33

0.613b

<0.001

0.380a

0.029

     
  1. Note: AC Adults with Cancer, FC Family Caregivers, Anx Anxiety, Dep Depression, Correlation of Anx Correlation of Anx between adults with cancer and their family caregivers, Correlation of Dep Correlation of Dep between adults with cancer and their family caregivers
  2. aCorrelation is significant at the 0.05 level (2-tailed)
  3. bCorrelation is significant at the 0.01 level (2-tailed)
  4. cThe total n does not equal 641 because of missing values