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Table 2 Intervention Program Effects. Results from regression adjusted by baseline HRQoL centred in the mean

From: Health related quality of life improvement in chronic non-specific neck pain: secondary analysis from a single blinded, randomized clinical trial

Health related quality of life (SF-36)

aControl group (n = 64) Mean(SE)

aDDN group (n = 64) Mean(SE)

bMean diff.

95% Confidence Interval

P-value

Physical Function

 A1 - A0

−4.36 (1.91)

6.54 (1.91)

10.9

(5.5 to 16.3)

0.00011

 A2 - A0

0.52 (1.36)

7.44 (1.36)

6.92

(3.08 to 10.76)

0.00052

 A3 - A0

−3.5 (2.01)

8.45 (2.01)

11.95

(6.28 to 17.62)

0.00006

 A4 - A0

−4.19 (1.84)

7.64 (1.84)

11.83

(6.62 to 17.04)

0.00002

Physical Role

 A1 - A0

0.64 (0.9)

7.95 (0.9)

7.31

(4.8 to 9.82)

0.00000

 A2 - A0

2.76 (1.02)

8.57 (1.02)

5.81

(2.95 to 8.68)

0.00010

 A3 - A0

1.46 (1.28)

9.87 (1.28)

8.41

(4.82 to 11.99)

0.00001

 A4 - A0

0.75 (1.1)

8.33 (1.1)

7.58

(4.51 to 10.65)

0.00000

Bodily Pain

 A1 - A0

5.59 (2.55)

12.81 (2.55)

7.22

(−0.08 to 14.52)

0.05241

 A2 - A0

6.97 (2.38)

13.08 (2.38)

6.11

(−0.72 to 12.94)

0.07890

 A3 - A0

−1.11 (2.95)

11.52 (2.95)

12.63

(4.2 to 21.07)

0.00364

 A4 - A0

4.54 (2.76)

13.31 (2.76)

8.77

(0.86 to 16.69)

0.03012

General Health

 A1 - A0

−0.82 (1.44)

4.16 (1.44)

4.98

(0.93 to 9.02)

0.01644

 A2 - A0

−1.3 (1.57)

2.58 (1.57)

3.87

(−0.52 to 8.27)

0.08381

 A3 - A0

1.55 (1.74)

5.46 (1.74)

3.91

(−0.97 to 8.79)

0.11564

 A4 - A0

−2.27 (1.58)

3.77 (1.58)

6.04

(1.62 to 10.46)

0.00783

Vitality

 A1 - A0

4.96 (1.96)

15.58 (1.96)

10.61

(5.11 to 16.12)

0.00021

 A2 - A0

2.94 (1.91)

12.07 (1.91)

9.13

(3.77 to 14.49)

0.00099

 A3 - A0

5.89 (2.13)

15.43 (2.13)

9.53

(3.56 to 15.51)

0.00199

 A4 - A0

−0.91 (2.27)

16.28 (2.27)

17.19

(10.84 to 23.55)

0.00000

Social Function

 A1 - A0

−3.75 (1.89)

8.83 (1.89)

12.58

(7.3 to 17.86)

0.00001

 A2 - A0

0.33 (1.96)

9.63 (1.96)

9.31

(3.82 to 14.8)

0.00105

 A3 - A0

3.41 (1.69)

9.09 (1.69)

5.69

(0.97 to 10.41)

0.01856

 A4 - A0

−6.92 (2.2)

11.61 (2.2)

18.53

(12.37 to 24.69)

0.00000

Emotional Role

 A1 - A0

0.51 (0.87)

3.13 (0.87)

2.62

(0.17 to 5.07)

0.03654

 A2 - A0

3.52 (0.92)

5.34 (0.92)

1.82

(−0.75 to 4.39)

0.16409

 A3 - A0

1.19 (0.92)

4.93 (0.92)

3.75

(1.18 to 6.32)

0.00463

 A4 - A0

−0.27 (1.07)

3.79 (1.07)

4.06

(1.06 to 7.06)

0.00831

Mental Health

 A1 - A0

1.43 (1.97)

10.81 (1.97)

9.38

(3.82 to 14.94)

0.00116

 A2 - A0

4.63 (1.6)

6.15 (1.6)

1.53

(−3.25 to 6.3)

0.52731

 A3 - A0

9.6 (1.49)

11.26 (1.49)

1.66

(−2.87 to 6.19)

0.46848

 A4 - A0

5.71 (1.71)

11.05 (1.71)

5.34

(0.38 to 10.3)

0.03498

SF-36 PSC

 A1 - A0

1.61 (0.65)

2.25 (0.65)

0.64

(−1.17 to 2.46)

0.48401

 A2 - A0

0.48 (0.65)

1.8 (0.65)

1.31

(−0.58 to 3.21)

0.17201

 A3 - A0

−1.41 (0.86)

1.86 (0.86)

3.26

(0.69 to 5.84)

0.01358

 A4 - A0

−1.22 (0.75)

1.92 (0.75)

3.14

(0.96 to 5.31)

0.00512

SF-36 MCS

 A1 - A0

0.3 (0.87)

4.25 (0.87)

3.95

(1.5 to 6.39)

0.00185

 A2 - A0

1.71 (0.58)

3.1 (0.58)

1.38

(−0.36 to 3.12)

0.11917

 A3 - A0

4.04 (0.66)

4.8 (0.66)

0.75

(−1.25 to 2.76)

0.45702

 A4 - A0

0.59 (0.75)

4.83 (0.75)

4.24

(2.07 to 6.41)

0.00018

  1. SE standard error; VX-V0 model for differences in the corresponding SF-36 dimension between visit 0 and visit X;
  2. aExpected change of SF-36 score between visits in a participant with average score at baseline;
  3. bExpected Mean Difference between groups; SF-36 PSC: Physical Component Summary; SF-36 MSC: Mental Component Summary
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Health and Quality of Life Outcomes

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