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Table 2 Mean change in SF-36-PFS scores from baseline to 6-month follow-up for each level of the CGI response

From: Defining the minimally clinically important difference of the SF-36 physical function subscale for paediatric CFS/ME: triangulation using three different methods

Clinical Global Impression at 6 months’ follow-up SF-36-PFS change between baseline and 6-months’ follow-up
Median (IQR) Mean (95% CI) SD n
Very much better 30 (20, 40) 33.1 (25.1, 41.0) 19.3 25
Much better 20 (5, 35) 20.1 (14.8, 25.5) 22.3 69
A little better 10 (−5, 20) 8.8 (3.9, 13.7) 20.1 67
No change 0 (−12, 15) −0.9 (−11.9, 10.1) 18.2 13
A little worse 7 (−10, 10) 3.8 (−9.9, 17.6) 22.7 13
Much worse −15 (−20, 5) −6.8 (− 20.5, 6.9) 17.8 9
Very much worse −25 (−40, −10) −25.0 (− 215.6, 165.6) 21.2 2