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Table 2 Mean change in SF-36-PFS scores from baseline to 6-month follow-up for each level of the CGI response

From: Defining the minimally clinically important difference of the SF-36 physical function subscale for paediatric CFS/ME: triangulation using three different methods

Clinical Global Impression at 6 months’ follow-up

SF-36-PFS change between baseline and 6-months’ follow-up

Median (IQR)

Mean (95% CI)

SD

n

Very much better

30 (20, 40)

33.1 (25.1, 41.0)

19.3

25

Much better

20 (5, 35)

20.1 (14.8, 25.5)

22.3

69

A little better

10 (−5, 20)

8.8 (3.9, 13.7)

20.1

67

No change

0 (−12, 15)

−0.9 (−11.9, 10.1)

18.2

13

A little worse

7 (−10, 10)

3.8 (−9.9, 17.6)

22.7

13

Much worse

−15 (−20, 5)

−6.8 (− 20.5, 6.9)

17.8

9

Very much worse

−25 (−40, −10)

−25.0 (− 215.6, 165.6)

21.2

2