Skip to main content

Table 5 Convergent and discriminant validity (Spearman rho) for HS-FOCUS total scores with validated CHQ and HUI3

From: Validation of the shortened Hunter Syndrome-Functional Outcomes for Clinical Understanding Scale (HS-FOCUS)

Instrument

Domain

Caregiver-reported patients (3–26 years)

n = 31

Self-reported patients (12–17 years)

n = 7

Self-reported patients (18–58 years)

n = 13

CHQa

Physical functioning

−0.83*

− 0.58

Role/social–emotional (E)/behavioral (B)

−0.16

−0.80 (E), –0.09 (B)

Role/social–physical

−0.68*

−0.89

Bodily pain

−0.51

−0.45

Behavior

0.38

Global behavior

0.22

−0.29

Mental health

−0.01

−0.39

Self-esteem

−0.28

−0.14

General health perceptions

−0.45

−0.21

Change in health

−0.08

−0.23

Parental impact-time

−0.01

Parental impact-emotional

−0.04

Family activities

−0.22

−0.53

Family cohesion

−0.22

−0.64

HUI3

Vision

−0.21

−0.29

− 0.46

Hearing

−0.32

−0.67

− 0.10

Speech

−0.66*

−0.84

− 0.50

Ambulation

−0.72*

0.13

−0.87§

Dexterity

−0.73*

−0.87

− 0.70

Emotion

−0.42

−0.65

− 0.16

Cognition

−0.55

−0.85

− 0.08

Pain

−0.52

0.13

−0.80

  1. Spearman’s rho significance levels: *p < 0.0001; p < 0.05; p < 0.01; §p < 0.001
  2. aSelf-reported patients (12–18 years of age) completed the CHQ Child form (CHQ-CF) and caregivers completed the CHQ Parent form (CHQ-PF) on behalf of caregiver-reported patients (of any age)
  3. Abbreviations: CHQ Child Health Questionnaire, HS-FOCUS Hunter Syndrome-Functional Outcomes for Clinical Understanding Scale, HUI3 Health Utility Index Mark 3