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Table 3 Gross Motor Function Measure (GMFM) and muscle tone before and 6 months after stem cell transplantation

From: The effects of bone marrow mononuclear cell transplantation on the quality of life of children with cerebral palsy

 

Baseline

6 months posttransplantation

Mean difference

Mean±SD

Mean±SD

[95% CI]

Total GMFM-88

21.71±10.06

40.03±14.79

18.32 [14.99; 21.64] ***

A. Lying & Rolling

16.27±9.26

37.59±17.09

21.31 [16.83; 25.79] ***

B. Sitting

12.56±10. 46

30.51±19.60

17.94 [12.20; 23.69] ***

C. Crawling & Kneeling

8.15± 6.64

22.23±19.69

14.08 [8.02; 20.13] ***

D. Standing

3.74±2.35

13.78±9.69

10.04 [4.08; 15.99] **

E. Walking, Running & Jumping

2.28±1.54

5.70±4.62

3.41 [0.22; 6.60] *

GMFM-66 Percentiles

29.76±16.68

74.96± 24.40

45.2 [35.93; 54.46] ***

Modified Ashworth Score

3.77±0.68

2.16±0.70

−1.60 [− 1.84; − 1.37] ***

  1. ***P-value < 0.0001 (paired t-test, compared to baseline)
  2. **P-value < 0.001 (paired t-test, compared to baseline)
  3. *P-value< 0.05 (paired t-test, compared to baseline)