Variables | OR univariate [95% CI] | OR multivariate [95% CI] |
---|---|---|
Demographic variables | ||
Age (years) | 1.01 [0.96–1.06] | |
Male | 0.85 [0.22–3.22] | |
Health-related variables | ||
BMI (kg/m2) | 1.05 [0.96–1.14] | |
Smoking (pack-years) | 1.00 [0.99–1.02] | |
Dyspnea (≥ 2 mMRC) | 5.09 [2.06–12.55]** | 5.62 [1.98–15.93]** |
Exacerbationsa (≥2) | 1.60 [0.66–3.88] | |
Comorbilidities (≥ 4) | 1.02 [0.43–2.46] | |
FEV1% predicted | 0.99 [0.97–1.02] | |
FVC % predicted | 0.98 [0.96–1.01] | |
Anxiety (HADS-A ≥ 11) | 8.48 [2.84–25.34]** | |
Depression (HADS-D ≥ 11) | 20.78 [5.18–83.28]** | 22.63 [5.0–102.32]** |