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Table 3 Demographic data and responses regarding urinary, bowel and sexual function and bother to the UCLA-PCI of the participants of the Pros-IT CNR study at the time they were diagnosed with prostate cancer

From: Disease-specific and general health-related quality of life in newly diagnosed prostate cancer patients: the Pros-IT CNR study

 

Urinary Function*

p-value

Urinary Bother*

p-value

Bowel Function*

p-value

Bowel Bother*

p-value

Sexual Function*

p-value

Sexual Bother*

p-value

Age at diagnosis

 

0.0015§

 

0.0030§

 

0.0058§

 

0.0167§

 

< 0.0001§

 

< 0.0001§

  < 60 years

95.5 ± 12.4

 

93.3 ± 18.1

 

94.7 ± 12.4

 

94.9 ± 17.5

 

74.3 ± 25.0

 

74.8 ± 34.6

 

 60–64

94.3 ± 14.2

 

88.7 ± 23.7

 

94.5 ± 13.4

 

94.3 ± 15.7

 

63.2 ± 27.8

 

66.9 ± 34.6

 

 65–69

93.3 ± 16.3

 

88.9 ± 23.5

 

94.7 ± 11.4

 

94.6 ± 16.0

 

51.2 ± 30.4

 

65.3 ± 32.8

 

 70–74

92.2 ± 16.6

 

86.9 ± 24.5

 

92.9 ± 13.7

 

92.1 ± 19.6

 

43.1 ± 30.2

 

59.5 ± 35.1

 

 75–79

92.3 ± 16.3

 

87.5 ± 24.2

 

92.8 ± 13.9

 

93.3 ± 18.9

 

33.2 ± 29.5

 

58.5 ± 36.4

 

 80+

92.2 ± 16.7

 

88.0 ± 23.9

 

91.9 ± 16.2

 

87.1 ± 25.1

 

23.0 ± 25.3

 

70.3 ± 33.6

 

Education

 

0.8255

 

0.7833

 

0.3867

 

0.1411

 

0.2339

 

0.4686

 University degree

94.3 ± 14.2

 

89.3 ± 22.1

 

95 ± 11.2

 

93.1 ± 17.2

 

56.8 ± 32.6

 

67.7 ± 35.3

 

 High school diploma

93.6 ± 15.4

 

88.2 ± 23.8

 

93.4 ± 13

 

92.8 ± 18.7

 

52.2 ± 31.8

 

63.6 ± 35.2

 

 Lower secondary school diploma

92.8 ± 15.7

 

88.9 ± 23.5

 

94.4 ± 12.4

 

94.5 ± 16.9

 

49.6 ± 32.5

 

66.2 ± 34.3

 

 Elementary or less

92.4 ± 16.8

 

88.3 ± 23.4

 

92.8 ± 14.7

 

92.9 ± 19.3

 

39.9 ± 30.5

 

61.8 ± 35.2

 

Marital status

 

0.1720

 

0.6739

 

0.0158

 

0.6490

 

0.5433

 

0.6904

 Married/cohabiting

93.4 ± 15.6

 

88.7 ± 23.2

 

93.9 ± 13.1a

 

93.5 ± 18.1

 

49.1 ± 32.2

 

63.9 ± 35.1

 

 Widowed

91.7 ± 15

 

88.7 ± 22.9

 

92.7 ± 14.2

 

91.1 ± 21.9

 

40.6 ± 29.9

 

63.3 ± 34.5

 

 Separated, divorced, single

91.9 ± 17.1

 

87.1 ± 25.1

 

91.5 ± 13.9a

 

93 ± 18.3

 

48.4 ± 32.7

 

66.6 ± 34.8

 

Geographical residence

 

0.0792

 

0.0988

 

0.1680

 

0.2818

 

0.0651

 

< 0.0001

 North Italy

93.2 ± 15.3

 

88.3 ± 23.2

 

93.5 ± 12.8

 

93.1 ± 18.3

 

47.5 ± 32.3

 

67.8 ± 34.1ab

 

 Central Italy

92.7 ± 16.5

 

90.2 ± 22.1

 

94.7 ± 12.3

 

94.2 ± 17.6

 

51.4 ± 31.3

 

58.8 ± 35.3a

 

 South Italy

92.5 ± 16

 

86.9 ± 25.5

 

93 ± 14.9

 

92.8 ± 19.1

 

46.7 ± 33.2

 

60 ± 36.3b

 

BMI

 

0.8219

 

0.3962

 

0.0290

 

0.6373

 

0.0012

 

0.3423

 Under/normal weight (< 25 kg/m2)

93 ± 16.2

 

88.7 ± 23.9

 

94 ± 12.6a

 

93.3 ± 18.3

 

50.3 ± 32a

 

65.3 ± 34.8

 

 Overweight (25–29.9 kg/m2)

93.1 ± 15.6

 

88.7 ± 22.9

 

94.1 ± 12.5b

 

93.6 ± 17.6

 

48.9 ± 32.3b

 

64.1 ± 34.8

 

 Obesity (≥30 kg/m2)

93.3 ± 15.1

 

87.4 ± 23.7

 

91 ± 16.5ab

 

91.8 ± 21.0

 

43.4 ± 32ab

 

61.8 ± 36.1

 

Smoking status

 

0.3011

 

0.2375

 

0.5201

 

0.8061

 

0.6522

 

0.9697

 Non-smoker or former

92.9 ± 16

 

88.1 ± 23.9

 

93.4 ± 13.5

 

93.1 ± 18.6

 

47.8 ± 32.2

 

63.8 ± 35.2

 

 Current smoker

94.4 ± 14.3

 

91.1 ± 20.4

 

94.7 ± 11.3

 

93.9 ± 16.6

 

53.6 ± 31.2

 

66.1 ± 34.0

 

Diabetes mellitus

 

0.3837

 

0.2607

 

0.6216

 

0.0585

 

< 0.0001

 

0.6154

 No

93.3 ± 15.7

 

88.9 ± 23.0

 

93.8 ± 12.9

 

93.7 ± 17.7

 

50.5 ± 32.0

 

64.5 ± 34.9

 

 Yes

92.6 ± 15.9

 

86.9 ± 25.0

 

92.9 ± 14.6

 

91.1 ± 21.4

 

38.2 ± 31.0

 

62.0 ± 35.7

 

N. of moderate/severe comorbidities (CIRS)

 

0.0774

 

0.0072

 

0.0001

 

< 0.0001

 

< 0.0001

 

0.1873

 0–2

93.4 ± 15.5

 

89.4 ± 22.3

 

94.2 ± 12.5

 

94.5 ± 16.3

 

50.8 ± 31.9

 

64.9 ± 34.9

 

 3+

91.9 ± 16.6

 

83.8 ± 27.8

 

90.3 ± 16.3

 

86.5 ± 26.1

 

35.7 ± 30.7

 

60.2 ± 35.4

 

T staging at diagnosis

 

0.1070

 

0.0133

 

0.2658

 

0.5184

 

< 0.0001

 

0.4077

 T1

94.2 ± 14

 

90.3 ± 22

 

94.6 ± 12.2

 

94 ± 17.2

 

55.7 ± 30.6a

 

66.6 ± 33.8

 

 T2

92.8 ± 16.2

 

87.2 ± 24.4

 

93.6 ± 13.0

 

93.0 ± 18.3

 

43.5 ± 31.7b

 

62.8 ± 34.8

 

 T3 or T4

90.7 ± 19

 

86.4 ± 24.3

 

93.5 ± 13.6

 

93.2 ± 19.5

 

37.1 ± 32.3ab

 

63.6 ± 36.9

 

Gleason score at diagnosis

 

0.6653

 

0.2894

 

0.8231

 

0.5100

 

< 0.0001

 

0.5015

 6

93.9 ± 14.4

 

90.1 ± 21.6

 

94.3 ± 12.2

 

94.3 ± 16.6

 

54.8 ± 30.3

 

66.0 ± 34.1

 

 3 + 4

93.3 ± 16.4

 

88.9 ± 23.3

 

93.8 ± 12.5

 

92.8 ± 18.3

 

48.8 ± 31.7

 

62.7 ± 35.5

 

 4 + 3

93.7 ± 13.4

 

86.7 ± 25.0

 

93.4 ± 13.1

 

93.8 ± 17.0

 

44.9 ± 32.5

 

60.6 ± 35.9

 

 8+

91.6 ± 18.5

 

87.1 ± 24.8

 

93 ± 14.7

 

92.1 ± 21.2

 

39 ± 33.3

 

64.5 ± 35.7

 
  1. *mean ± SD
  2. §p-value from test for trend
  3. a, bsignificant post-hoc (p < 0.05 adjusting for age at diagnosis