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Table 4 Association of PA and QOL - Active vs. non-active

From: Quality of life and physical activity in long-term (≥5 years post-diagnosis) colorectal cancer survivors - systematic review

  Statistical significance (p <0.05) and clinical relevance
+/−: significant positive/negative association
ns: not statistically significant
.: not reported
a,b,cclinical relevance
Study C30 QL PF RF EF SF CF
Husson 2015 [34] Meeting vs. not meeting ACS PA guideline, Interindividuald +b +b +b +b +b +
Meeting vs. not meeting ACS PA guideline, Intraindividuale + + + ns ns ns
Mols 2015 [9] Meeting vs. not meeting ACS PA guideline +c +c +c +c +c +c
Study SF-36 PF RP BP SF MH RE VT GH GCS PCS MCS
Blanchard 2004 [35] Meeting vs. not meeting ACS PA guideline . . . . . . . . +c . .
Blanchard 2008 [30] Meeting vs. not meeting ACS PA guideline . . . . . . . . +c . .
Thraen-Borowski 2013 [37] Meeting vs. not meeting ACS PA guideline +a +a + +a ns ns +a +a . . .
Study FACT-C/ SWLS PWB SWB EWB FWB CCS SWLS
Chambers 2012 [38] Sedentary - Ref.
Insufficiently active (1–149 min/wk)
ns ns ns ns ns ns
Sufficiently active (≥150 min/wk) ns ns ns ns ns ns
Study PROMIS/ EQ-5D Physical HRQOL Mental HRQOL Overall HRQOL
Rodriguez 2015 [36] PA min/wk
No PA - Ref.
≤60, 61–149, 150–249, 250+
+c (≤60, 61–149, 150–249) ns +c (≤60, 61–149, 150–249)
  1. PA physical activity, QOL quality of life, C30 (European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire) QL global quality of life, PF physical functioning, RF role functioning, EF emotional functioning, SF social functioning, CF cognitive functioning, ACS PA guideline American Cancer Society physical activity recommendations of at least 150 min of MVPA per week, SF-36 (The Short Form Health Survey) PF physical functioning, RP role limitations due to physical health problems, BP bodily pain, SF social functioning, MH general mental health, RE role limitations due to emotional problems, VT vitality, GH general health perceptions, GCS global health composite score, PCS physical composite score, MCS mental composite score, FACT-C (Functional Assessment of Cancer Therapy - Colorectal Cancer) PWB physical well-being, SWB social well-being, EWB emotional well-being, FWB functional well-being, CCS colorectal cancer scale, SWLS (Satisfaction with Life Scale), Ref. Reference, min/wk minutes per week, PROMIS (Patient-Reported Outcomes Measurement Information System), EQ-5D (EuroQol Five-Dimension Questionnaire), aclinical relevance reported by authors; bclinical relevance calculated by RE; cclinical relevance: no values, no cut-off for calculation available; dinterindividual: patients average amount of PA/ average level PA of total group; eintraindividual: patients PA level at one time point/ patients average PA level