Table 6 SF-36: Important Change Score Estimates Using Distribution-based, Anchor-based, and Linking Methods
SF-36 Domain/Component Summary score | 1 SEM | 0.5 SD | Anemia 4–7, Week 9 | Anemia 4–7, Week 13/17 | Fatigue 3–5, Week 9 | Fatigue 3–5, Week 13/17 | Linking FACT-An total | Linking anemia | Linking fatigue |
|---|---|---|---|---|---|---|---|---|---|
Physical functioning | 4.6 | 5.5 | 2.6 | 2.9 | 1.5 | 2.3 | 2.59 | 2.96 | 2.90 |
Role-Physical | 6.2 | 5.6 | 1.7 | 2.4 | 1.0 | 0.7 | Â | Â | Â |
Vitality | 7.2 | 6.0 | 5.7 | 3.1 | 3.9 | 1.0 | 2.80 | 3.20 | 3.13 |
Role-Emotional | 7.0 | 6.9 | 2.9 | −1.3 | 3.7 | −2.4 |  |  |  |
Mental Health | 5.8 | 5.7 | 3.4 | −0.2 | 3.2 | 0.9 |  |  |  |
Social Functioning | 6.4 | 5.8 | 1.4 | 1.0 | 0.5 | −1.5 |  |  |  |
Bodily Pain | 5.7 | 5.6 | 2.1 | −1.4 | −0.2 | −3.0 |  |  |  |
General Health | 4.8 | 4.8 | 3.1 | −2.2 | − 1.5 | − 2.2 |  |  |  |
Physical Component Summary score | 4.2 | 4.7 | 2.0 | 1.5 | −0.8 | 0.0 | 2.19 | 2.51 | 2.45 |
Mental Component Summary score | 5.7 | 5.8 | 3.6 | −0.5 | 3.8 | −1.3 |  |  |  |