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Table 3 Internal Consistency and Test-retest Reliability of the SF-36 and the FACT-An Subscales

From: Measurement properties of the Short Form-36 (SF-36) and the Functional Assessment of Cancer Therapy - Anemia (FACT-An) in patients with anemia associated with chronic kidney disease

SF-36 domain/Component Summary score

Na

Cronbach’s alpha

Nb

Test-retest (ICC)

FACT-An total/subscale

Na

Cronbach’s alpha

Nb

Test-retest (ICC)

Physical functioning

188

0.90

77

0.83

Anemia subscale

190

0.92

76

0.83

Role-physical

193

0.93

76

0.69

Fatigue subscale

196

0.93

76

0.80

Vitality

193

0.82

75

0.64

Total FACT-An score

131

0.95

76

0.88

Role-Emotional

193

0.93

77

0.74

FACT-G score

133

0.91

76

0.86

Mental Health

193

0.81

77

0.75

Functional Well-Being

196

0.87

76

0.83

Social Functioning

194

0.76

77

0.69

Physical Well-Being subscale

196

0.84

76

0.83

Bodily Pain

194

0.88

77

0.74

Social Well-Being

137

0.80

76

0.76

General Health

192

0.69

77

0.75

Emotional Well-Being

193

0.79

76

0.72

Physical Component Summary score

–

0.92

76

0.81

     

Mental Component Summary score

–

0.90

76

0.75

     
  1. Abbreviations: ICC intraclass correlation coefficient, FACT-An Functional Assessment of Cancer Therapy-Anemia, FACT-G Functional Assessment of Cancer Therapy-General, SF-36 Medical Outcomes Survey Short Form-36
  2. a.Number of subjects at Baseline
  3. b.Number of subjects with average weekly Hb change within +/− 0.5 g/dL between Week 9 and Week 13/17 (study FGCL-4592-053/study FGCL-4592-041) and who have not received rescue therapy