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Table 1 Demographic, clinical and laboratory data of studied children

From: Health-related quality of life in pediatric and adolescent patients with transfusion-dependent ß-thalassemia in upper Egypt (single center study)

Parameters Patients Controls p-value
N = 64 N = 64
Age Range 8-18 8-18 0.16
Mean ± SD 12.1 ± 3.2 11.1 ± 2.8
median 10 12
Sex Male 43 (67.2%) 53 (82.8%) 0.15
female 21 (32.8%) 11 (17.2%)
Weight centile Range 5-90 25-95 0.001*
Mean ± SD 25.9 ± 18.5 63 ± 19.3
Median 30 55
Height centile Range 5-90 10-95 0.001*
Mean ± SD 15.7 ± 10.5 56.1 ± 22.8
Median 20 59
Head circumference centile Range 18-90 15-95 0.22
Mean ± SD 68.2 ± 19 63.2 ± 16.1
Median 75 79
Educational status: -Uneducated 20 (31.2%) 0(0%) 0.005*
-Primary school 31 (48.4%) 50 (78.1%)
-Secondary school 13 (20.4%) 14 (21.9%)
Household income < 500 EGP 15 (23.4%) 20 (30%) 0.02*
500-1000 34 (53.2%) 24 (40%)
> 1000 15 (23.4%) 20 (30%)
Age of start transfusion (month) Range 6-72
Mean ± SD 15.8 ± 11.8
Median 10.5
Age of start chelation Range 2-12
Mean ± SD 4.1 ± 2.6
Median 4
Type of chelation used No chelation 7 (10.9%)
Deferoxamine 20 (31.3%)
Deferoperone 13 (20.3%)
Desferosirax 24 (37.5%)
Liver enlargement Hepatomegaly 49 (76.6%)
No hepatomegaly 15 (23.4%)
Splenectomized No 34 (53.1%)
Yes 30 (46.9%)
Hepatitis C infection Positive 22 (34.4%)
Negative 42 (65.6%)
Hepatitis B infection Positive 0 (0%)
Negative 64 (100%)
Serum ferritin (ng/ml) Mean ± SD 975 ± 22.1 43 ± 3.7 0.001*
  1. *= Significant (p < 0.05)